SCHEMBL21245479

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL27523288	0.84	SLC1A1 (0.50)	SLC1A1FOLH1MMECA1CA2
	SCHEMBL4985838	0.81	CYP1A2 (0.55)	SLC1A1FOLH1CYP1A2
	SCHEMBL4989295	0.80	GRIK1 (0.47)	KMT2ACYP1A2
	SCHEMBL28225061	0.79	TACR1 (0.49)	SLC1A1CA1CA2CA7CA9
	SCHEMBL26330565	0.78	TSHR (0.52)	SLC1A1CA1CA2CA7CA9
	SCHEMBL5941636	0.78	SLC1A1 (0.61)	SLC1A1FOLH1CA1CA2CA7
	SCHEMBL5870182	0.78	FOLH1 (0.58)	SLC1A1FOLH1CA1CA2CA7
	SCHEMBL5941631	0.78	SLC1A1 (0.61)	SLC1A1FOLH1CA1CA2CA7
	SCHEMBL11073343	0.78	SLC1A1 (0.55)	SLC1A1FOLH1KMT2A
	SCHEMBL10812169	0.78	SLC1A1 (0.55)	SLC1A1FOLH1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.