Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP14 | P50281 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL392233 | 0.90 | LMNA (0.54) | ALDH1A1SLC1A1CA1KMT2ACA2 | |
| SCHEMBL1195693 | 0.88 | KMT2A (0.49) | ALDH1A1SLC1A1CA1KMT2ACA2 | |
| SCHEMBL4909047 | 0.88 | KMT2A (0.49) | ALDH1A1SLC1A1CA1KMT2ACA2 | |
| SCHEMBL4906646 | 0.88 | KMT2A (0.49) | ALDH1A1SLC1A1CA1KMT2ACA2 | |
| SCHEMBL27515184 | 0.88 | ALDH1A1 (0.46) | ALDH1A1SLC1A1CA1KMT2ACA2 | |
| SCHEMBL8929852 | 0.86 | ALDH1A1 (0.55) | ALDH1A1CA1KMT2ACA2CA7 | |
| SCHEMBL1708896 | 0.86 | ALDH1A1 (0.55) | ALDH1A1CA1KMT2ACA2CA7 | |
| SCHEMBL25640234 | 0.86 | ALDH1A1 (0.55) | ALDH1A1CA1KMT2ACA2CA7 | |
| SCHEMBL800946 | 0.86 | SLC1A1 (0.55) | ALDH1A1SLC1A1CA1KMT2ACA2 | |
| SCHEMBL7494382 | 0.86 | SLC1A1 (0.55) | ALDH1A1SLC1A1CA1KMT2ACA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019152688-A1 | SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF | APTINYX INC. (US) | 2019-08-08 | — | — | WO | disclosed |