Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22754564 | 0.91 | MMP13 (0.56) | MMP13ALDH1A1KMT2AHPGDLMNA | |
| SCHEMBL21246546 | 0.83 | ALDH1A1 (0.63) | ALDH1A1KMT2AMEN1KCNJ1HTT | |
| SCHEMBL29437165 | 0.83 | ALDH1A1 (0.63) | ALDH1A1KMT2AMEN1KCNJ1HTT | |
| SCHEMBL21246566 | 0.82 | MMP13 (0.55) | MMP13ALDH1A1KMT2AHPGDLMNA | |
| SCHEMBL21246551 | 0.82 | HPGD (0.58) | MMP13ALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL29437161 | 0.76 | MMP13 (0.85) | MMP13ALDH1A1KMT2AHPGDLMNA | |
| SCHEMBL13102334 | 0.76 | MMP13 (0.85) | MMP13ALDH1A1KMT2AHPGDLMNA | |
| SCHEMBL28716909 | 0.76 | MMP13 (0.54) | MMP13ALDH1A1KMT2AHPGDLMNA | |
| SCHEMBL3364526 | 0.75 | GAA (0.69) | MMP13ALDH1A1HPGDLMNAPOLB | |
| SCHEMBL21246615 | 0.74 | NPC1 (0.60) | MMP13ALDH1A1KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019149223-A1 | BENZAMIDE COMPOUND AND PREPARATION METHOD, USE, AND PHARMACEUTICAL COMPOSITION THEREOF | 中国医学科学院药物研究所 | 2019-08-08 | — | — | WO | disclosed |