Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | NSD2 | O96028 | 1/20 | 0.53 |
| ▸ | CASP6 | P55212 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | CASP9 | P55211 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | PGK1 | P00558 | 1/20 | 0.38 |
| ▸ | ADCY10 | Q96PN6 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29058365 | 0.93 | KDM4E (0.53) | KDM4EMAPTALDH1A1NSD2CASP6 | |
| SCHEMBL26124927 | 0.88 | KDM4E (0.41) | KDM4EMAPTALDH1A1NSD2CASP6 | |
| SCHEMBL29313505 | 0.79 | KDM4E (0.46) | KDM4EMAPTALDH1A1NSD2SMN1; SMN2 | |
| SCHEMBL30665076 | 0.79 | ALDH1A1 (0.55) | KDM4EMAPTALDH1A1NSD2SMN1; SMN2 | |
| SCHEMBL25104925 | 0.78 | ALDH1A1 (0.53) | KDM4EMAPTALDH1A1NSD2MEN1 | |
| SCHEMBL17396160 | 0.78 | KDM4E (0.53) | KDM4EMAPTALDH1A1NSD2MAOA | |
| SCHEMBL29109564 | 0.78 | MAPT (0.53) | KDM4EMAPTALDH1A1NSD2MEN1 | |
| Hydrochloric Acid SCHEMBL31600876 | 0.78 | ALDH1A1 (0.53) | KDM4EMAPTALDH1A1NSD2SMN1; SMN2 | |
| SCHEMBL29109563 | 0.78 | KDM4E (0.44) | KDM4EMAPTALDH1A1NSD2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL31600450 | 0.76 | KDM4E (0.51) | KDM4EMAPTALDH1A1NSD2MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 186 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116102500-B | Method for synthesizing 6-chloro-2-methyl-2H-indazole-5-amine | 广东莱佛士制药技术有限公司 | 2025-06-24 | — | — | CN | claimed |
| CN-119592640-A | Process for preparing nitroreduction products | 广东东阳光药业股份有限公司 | 2025-03-11 | — | — | CN | claimed |
| CN-119592532-A | Nitroreductase mutant, preparation method and application | 广东东阳光药业股份有限公司 | 2025-03-11 | — | — | CN | claimed |
| CN-116003324-B | Synthesis method of 6-chloro-2-methyl-2H-indazole-5-amine | 杭州澳赛诺医药技术有限公司 | 2024-11-12 | — | — | CN | claimed |
| CN-118271292-A | Synthesis method of drug for treating new crown drug Enxi Qu Wei raw material drug | 北京康立生医药技术开发有限公司 | 2024-07-02 | — | — | CN | claimed |
| CN-115108992-B | Preparation method of 6-chloro-2-methyl-2H-indazol-5-amine | 浙江手心制药有限公司 | 2024-05-31 | — | — | CN | claimed |
| CN-116589410-B | Synthesis method of 6-chloro-2-methyl-2H-indazole-5-amine | 济南国鼎医药科技有限公司 | 2024-05-03 | — | — | CN | claimed |
| CN-114920699-B | Method for preparing 6-chloro-2-methyl-2H-indazol-5-amine | 甘肃皓天科技股份有限公司 | 2024-03-19 | — | — | CN | claimed |
| WO-2024017178-A1 | SUBSTITUTED HYDANTOIN COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | AVITAR BIOSCIENCES, INC. (CN) | 2024-01-25 | — | — | WO | claimed |
| CN-117285468-A | Preparation method of Ensitrelivir intermediate | 重庆博腾制药科技股份有限公司 | 2023-12-26 | — | — | CN | claimed |
| CN-116102500-A | Method for synthesizing 6-chloro-2-methyl-2H-indazole-5-amine | 广东莱佛士制药技术有限公司 | 2023-05-12 | — | — | CN | claimed |
| CN-116003324-A | Synthesis method of 6-chloro-2-methyl-2H-indazole-5-amine | 杭州澳赛诺生物科技有限公司 | 2023-04-25 | — | — | CN | claimed |
| CN-115181066-A | Synthetic method of 6-chloro-2-methyl-2H-indazole-5-amine | 浙江宏元药业股份有限公司 | 2022-10-14 | — | — | CN | claimed |
| CN-115108992-A | Preparation method of 6-chloro-2-methyl-2H-indazole-5-amine | 浙江手心制药有限公司 | 2022-09-27 | — | — | CN | claimed |
| CN-217313427-U | 6-chloro-2-methyl-2H-indazole-5-amine condensation reaction dehydration device | 上海晋鲁医药科技有限公司 | 2022-08-30 | — | — | CN | claimed |
| CN-114920699-A | Method for preparing 6-chloro-2-methyl-2H-indazole-5-amine | 甘肃皓天化学科技有限公司 | 2022-08-19 | — | — | CN | claimed |
| CN-114835645-A | Preparation method of 6-chloro-2-methyl-2H-indazole-5-amine | 上海昊泓生物科技有限公司 | 2022-08-02 | — | — | CN | claimed |
| CN-114751894-A | Preparation method of oral medicine for treating neocoronary pneumonia | 苏州立新制药有限公司 | 2022-07-15 | — | — | CN | claimed |
| CN-114644621-A | Preparation method of oral medicine S-217622 for treating neocoronary pneumonia | 苏州立新制药有限公司 | 2022-06-21 | — | — | CN | claimed |
| CN-114605328-A | Preparation method of 6-chloro-2-methyl-2H-indazole-5-amine | 汉瑞药业(荆门)有限公司 | 2022-06-10 | — | — | CN | claimed |