Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NSD2 | O96028 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | STIM1 | Q13586 | 2/20 | 0.42 |
| ▸ | ORAI1 | Q96D31 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 3/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CD44 | P16070 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15730121 | 0.84 | KDM4E (0.52) | KDM4EMAPTNSD2ALDH1A1STIM1 | |
| SCHEMBL29109563 | 0.79 | KDM4E (0.44) | KDM4EMAPTNSD2ALDH1A1STIM1 | |
| SCHEMBL21246780 | 0.79 | KDM4E (0.53) | KDM4EMAPTNSD2ALDH1A1STIM1 | |
| SCHEMBL13980264 | 0.77 | MAPT (0.46) | KDM4EMAPTNSD2ALDH1A1STIM1 | |
| SCHEMBL724583 | 0.77 | MAPT (0.46) | KDM4EMAPTNSD2ALDH1A1STIM1 | |
| SCHEMBL24163113 | 0.77 | MAPT (0.46) | KDM4EMAPTNSD2ALDH1A1STIM1 | |
| SCHEMBL27138498 | 0.77 | KDM4E (0.55) | KDM4EMAPTNSD2ALDH1A1STIM1 | |
| SCHEMBL29109591 | 0.77 | PGK1 (0.44) | KDM4EMAPTNSD2ALDH1A1MAOA | |
| SCHEMBL26485741 | 0.77 | NOTUM (0.38) | KDM4EALDH1A1POLBKMT2ACD44 | |
| SCHEMBL24930081 | 0.77 | KDM4E (0.42) | KDM4EMAPTNSD2ALDH1A1STIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4400502-A2 | TRIAZINE DERIVATIVES HAVING VIRUS REPLICATION INHIBITORY ACTIVITY AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Shionogi & Co., Ltd (JP) | 2024-07-17 | — | — | EP | disclosed |