Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PTPRC | P08575 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11175255 | 0.86 | ALDH1A1 (0.64) | MAPTALDH1A1L3MBTL1NPSR1RAB9A | |
| SCHEMBL412227 | 0.86 | ALDH1A1 (0.64) | MAPTALDH1A1L3MBTL1NPSR1RAB9A | |
| SCHEMBL30958374 | 0.84 | MAPT (0.67) | MAPTALDH1A1L3MBTL1NPSR1RAB9A | |
| SCHEMBL607022 | 0.84 | MAPT (0.67) | MAPTALDH1A1L3MBTL1NPSR1RAB9A | |
| SCHEMBL5038433 | 0.84 | ALDH1A1 (0.62) | MAPTALDH1A1L3MBTL1NPSR1RAB9A | |
| SCHEMBL6191307 | 0.84 | MAPT (0.62) | MAPTALDH1A1L3MBTL1NPSR1RAB9A | |
| Hydrochloric Acid SCHEMBL30684981 | 0.82 | MAPT (0.65) | MAPTALDH1A1L3MBTL1NPSR1RAB9A | |
| SCHEMBL12856701 | 0.82 | PTPRC (0.56) | MAPTALDH1A1L3MBTL1NPSR1RAB9A | |
| SCHEMBL5944124 | 0.81 | ALDH1A1 (0.73) | MAPTALDH1A1L3MBTL1NPSR1RAB9A | |
| SCHEMBL10029700 | 0.80 | MAPT (0.59) | MAPTALDH1A1L3MBTL1NPSR1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111433357-B | Alcohol dehydrogenase mutant and application thereof in synthesis of diaryl chiral alcohol | 江南大学 | 2022-11-11 | — | — | CN | disclosed |
| CN-111433357-A | Alcohol dehydrogenase mutant and application thereof in synthesis of diaryl chiral alcohol | 江南大学 | 2020-07-17 | — | — | CN | disclosed |
| WO-2019153634-A1 | ALCOHOL DEHYDROGENASE MUTANT AND APPLICATION THEREOF IN SYNTHESIS OF BIARYL CHIRAL ALCOHOL | 江南大学 | 2019-08-15 | — | — | WO | disclosed |
| WO-2019153632-A1 | ALCOHOL DEHYDROGENASE MUTANT AND APPLICATION THEREOF IN SYNTHEISIS OF DIARYL CHIRAL ALCOHOL | 江南大学 | 2019-08-15 | — | — | WO | disclosed |
| WO-2019153633-A1 | ALCOHOL DEHYDROGENASE MUTANT AND APPLICATION THEREOF IN SYNTHEISIS OF DIARYL CHIRAL ALCOHOL | 江南大学 | 2019-08-15 | — | — | WO | disclosed |