Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
| ▸ | ABCC1 | P33527 | 4/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.44 |
| ▸ | TLR2 | O60603 | 9/20 | 0.43 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.40 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6315699 | 0.68 | PTPN1 (0.54) | ABCC1ABCG2CXCR2 | |
| SCHEMBL21250154 | 0.67 | KMT2A (0.62) | KMT2AMEN1CNR2NOD1TLR2 | |
| SCHEMBL6120984 | 0.63 | ALDH1A1 (0.42) | KMT2AMEN1ABCC1ABCG2 | |
| SCHEMBL21603891 | 0.63 | ABCC1 (0.64) | CNR2ABCC1ABCG2CXCR2 | |
| SCHEMBL21260646 | 0.61 | ABCC1 (0.62) | ABCC1ABCG2CXCR2 | |
| Water SCHEMBL21597829 | 0.60 | ABCC1 (0.60) | ABCC1ABCG2CXCR2 | |
| SCHEMBL17909966 | 0.59 | ALDH1A1 (0.44) | KMT2AMEN1ABCC1ABCG2 | |
| SCHEMBL21247237 | 0.59 | CXCR2 (0.71) | KMT2AMEN1ABCC1ABCG2CXCR2 | |
| SCHEMBL6437345 | 0.59 | ALDH1A1 (0.68) | KMT2AMEN1ABCC1POLB | |
| SCHEMBL20541804 | 0.58 | FLT3 (0.75) | KMT2AMEN1ABCC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3749658-A1 | FUSED THIOPHENE DERIVATIVES AND THEIR USES | ENYO Pharma (FR) | 2020-12-16 | — | — | EP | disclosed |
| WO-2019154949-A1 | FUSED THIOPHENE DERIVATIVES AND THEIR USES | ENYO PHARMA (FR) | 2019-08-15 | — | — | WO | disclosed |