Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL871282 | 0.92 | PDK2 (0.37) | KMT2APDK2CA1CA2ALDH1A1 | |
| SCHEMBL3107680 | 0.90 | PDK2 (0.39) | KMT2AATMPDK2GRM2 | |
| SCHEMBL31529411 | 0.88 | ALDH1A1 (0.37) | KMT2AATMPDK2GRM2ALDH1A1 | |
| SCHEMBL31529413 | 0.88 | ALDH1A1 (0.37) | KMT2AATMPDK2GRM2ALDH1A1 | |
| SCHEMBL871262 | 0.88 | PDK2 (0.40) | KMT2APDK2CA1CA2 | |
| SCHEMBL20017082 | 0.88 | PDK2 (0.36) | KMT2AATMPDK2GRM2ALDH1A1 | |
| SCHEMBL18415106 | 0.87 | KMT2A (0.36) | KMT2AATMPDK2CA1CA2 | |
| SCHEMBL21248273 | 0.86 | CA1 (0.32) | CA1CA2 | |
| SCHEMBL21248275 | 0.86 | CA1 (0.32) | CA1CA2 | |
| SCHEMBL30394967 | 0.86 | CA1 (0.32) | CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12137688-B2 | Naphthalene isoxazoline compounds for controlling invertebrate pests | FMC CORPORATION (US) | 2024-11-12 | — | — | US | disclosed |
| US-20230157293-A1 | NAPHTHALENE ISOXAZOLINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS | FMC CORPORATION | 2023-05-25 | — | — | US | disclosed |
| US-11576382-B2 | Naphthalene isoxazoline compounds for controlling invertebrate pests | FMC CORPORATION (US) | 2023-02-14 | — | — | US | disclosed |
| US-20210045388-A1 | NAPHTHALENE ISOXAZOLINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS | FMC CORPORATION | 2021-02-18 | — | — | US | disclosed |
| EP-3752502-A1 | NAPHTHALENE ISOXAZOLINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS | FMC CORPORATION (US) | 2020-12-23 | — | — | EP | disclosed |
| WO-2019156903-A1 | NAPHTHALENE ISOXAZOLINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS | FMC CORPORATION (US) | 2019-08-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210045388-A1 | NAPHTHALENE ISOXAZOLINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS | RDX, RPS4X, CYP4X1 | KMT2A 1772/4885ATM 1267/4885PDK2 941/4885 |
| US-20230157293-A1 | NAPHTHALENE ISOXAZOLINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS | RDX, RPS4X, CYP4X1 | KMT2A 1772/4885ATM 1267/4885PDK2 941/4885 |
| US-11576382-B2 | Naphthalene isoxazoline compounds for controlling invertebrate pests | RDX, RPS4X, CYP4X1 | KMT2A 1772/4885ATM 1267/4885PDK2 941/4885 |
| US-12137688-B2 | Naphthalene isoxazoline compounds for controlling invertebrate pests | RDX, RPS4X, CYP4X1 | KMT2A 1772/4885ATM 1267/4885PDK2 941/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.