Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3630902 | 0.74 | LMNA (0.32) | SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL31255580 | 0.72 | LMNA (0.32) | SLC6A4SLC6A3 | |
| SCHEMBL17494386 | 0.67 | KDM4E (0.35) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL28776421 | 0.67 | KDM4E (0.35) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL19388032 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL28954176 | 0.66 | KDM4E (0.34) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL25434787 | 0.64 | LMNA (0.44) | — | |
| SCHEMBL21905026 | 0.64 | — | — | |
| SCHEMBL21592529 | 0.63 | — | — | |
| SCHEMBL29116142 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3752498-A1 | SOMATOSTATIN MODULATORS AND USES THEREOF | Crinetics Pharmaceuticals, Inc. (US) | 2020-12-23 | — | — | EP | disclosed |
| WO-2019157458-A1 | SOMATOSTATIN MODULATORS AND USES THEREOF | Crinetics Pharmaceuticals, Inc. (US) | 2019-08-15 | — | — | WO | disclosed |