SCHEMBL2124922

SCHEMBL2124922

C=CC(=O)OC(CCN=C=O)OC(=O)C=C

nearest known ligand 0.32

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.32
ALDH1A1 P00352 4/20 0.32
TP53 P04637 3/20 0.32
HIF1A Q16665 3/20 0.32
CYP3A4 P08684 2/20 0.32
MAPK1 P28482 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1850147 0.84 TSHR (0.32) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL1850146 0.83 TSHR (0.38) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL28562465 0.81 TSHR (0.34) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL5968584 0.77 TSHR (0.36) TSHRALDH1A1CYP3A4
SCHEMBL17868579 0.76 TSHR (0.47) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL25420322 0.76 TSHR (0.35) TSHRALDH1A1CYP3A4
SCHEMBL5163638 0.76 ALDH1A1 (0.30) TSHRALDH1A1CYP3A4
SCHEMBL9502020 0.75 TSHR (0.30) TSHR
SCHEMBL27774626 0.74 TSHR (0.34) TSHRALDH1A1CYP3A4
SCHEMBL27774624 0.74 TSHR (0.34) TSHRALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112904673-B Single-component photoresist composition, application thereof and touch screen comprising single-component photoresist composition 深圳市容大感光科技股份有限公司 2023-06-16 CN claimed
CN-112904673-A Single-component photoresist composition, use thereof and touch screen comprising same 深圳市容大感光科技股份有限公司 2021-06-04 CN claimed
CN-106883344-B Antifogging polymer, coating composition and preparation method thereof 湖南松井新材料股份有限公司 2020-10-23 CN claimed
WO-2019078621-A2 COATING COMPOSITION FOR PRODUCING ARTICLE HAVING SLIPPERY SURFACE 한양대학교 산학협력단 2019-04-25 WO claimed
EP-4342922-A1 FLUOROACRYLIC COMPOSITION, FLUOROCHEMICAL ACTINIC-RAY-CURABLE COMPOSITION, AND ARTICLE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-03-27 EP disclosed
CN-117321106-A Fluorine-containing acrylic composition, fluorine-containing active energy ray-curable composition, and article 信越化学工业株式会社 2023-12-29 CN disclosed
CN-112904673-B Single-component photoresist composition, application thereof and touch screen comprising single-component photoresist composition 深圳市容大感光科技股份有限公司 2023-06-16 CN disclosed
WO-2022244675-A1 FLUOROACRYLIC COMPOSITION, FLUOROCHEMICAL ACTINIC-RAY-CURABLE COMPOSITION, AND ARTICLE 信越化学工業株式会社 2022-11-24 WO disclosed
EP-3973007-A1 ORTHODONTIC ARTICLES COMPRISING POLYMERIZED COMPOSITION WITH PENDENT CYCLIC MOIETIES, METHODS, AND POLYMERIZABLE COMPOSITIONS 3M Innovative Properties Company (US) 2022-03-30 EP disclosed
CN-113980535-A Protective film forming film, composite sheet for protective film formation, and method for manufacturing semiconductor chip with protective film 琳得科株式会社 2022-01-28 CN disclosed
CN-112904673-A Single-component photoresist composition, use thereof and touch screen comprising same 深圳市容大感光科技股份有限公司 2021-06-04 CN disclosed
WO-2020234775-A1 ORTHODONTIC ARTICLES COMPRISING POLYMERIZED COMPOSITION WITH PENDENT CYCLIC MOIETIES, METHODS, AND POLYMERIZABLE COMPOSITIONS 3M INNOVATIVE PROPERTIES COMPANY (US) 2020-11-26 WO disclosed
CN-106883344-B Antifogging polymer, coating composition and preparation method thereof 湖南松井新材料股份有限公司 2020-10-23 CN disclosed
CN-106232575-B Carboxylic ester/urethane compound having polymerizable functional group and fluorine atom group, and method for producing same 优迈特株式会社 2020-02-21 CN disclosed
EP-3600634-A1 FILTER FOR SEPARATING HYDROPHILIC AND HYDROPHOBIC FLUIDS AND METHOD FOR THE PRODUCTION THEREOF Universität Innsbruck (AT) 2020-02-05 EP disclosed
WO-2019078621-A2 COATING COMPOSITION FOR PRODUCING ARTICLE HAVING SLIPPERY SURFACE 한양대학교 산학협력단 2019-04-25 WO disclosed
EP-2444436-A1 Water-dilutable modified alkyd resin compositions Cytec Austria GmbH (AT) 2012-04-25 EP disclosed
WO-2008105659-A1 RADIATION CURABLE RESIN COMPOSITION DSM IP ASSETS B.V. (NL) 2008-09-04 WO disclosed
EP-1812381-A1 ETHYLENICALLY UNSATURATED GROUP-CONTAINING ISOCYANATE COMPOUND AND PROCESS FOR PRODUCING THE SAME, AND REACTIVE MONOMER, REACTIVE (METH)ACRYLATE POLYMER AND ITS USE SHOWA DENKO KABUSHIKI KAISHA (JP) 2007-08-01 EP disclosed
WO-2006049264-A1 ETHYLENICALLY UNSATURATED GROUP-CONTAINING ISOCYANATE COMPOUND AND PROCESS FOR PRODUCING THE SAME, AND REACTIVE MONOMER, REACTIVE (METH)ACRYLATE POLYMER AND ITS USE SHOWA DENKO K.K. (JP) 2006-05-11 WO disclosed