SCHEMBL1850146

SCHEMBL1850146

C=CC(=O)OC(C)CCN=C=O

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.38
ALDH1A1 P00352 1/20 0.30
TP53 P04637 1/20 0.30
CYP3A4 P08684 1/20 0.30
MAPK1 P28482 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
HIF1A Q16665 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5968584 0.90 TSHR (0.36) TSHRALDH1A1CYP3A4HPGD
SCHEMBL25420322 0.89 TSHR (0.35) TSHRALDH1A1CYP3A4HPGD
SCHEMBL27774624 0.88 TSHR (0.34) TSHRALDH1A1CYP3A4HPGD
SCHEMBL28055435 0.88 TSHR (0.34) TSHRALDH1A1CYP3A4HPGD
SCHEMBL28055449 0.88 TSHR (0.34) TSHRALDH1A1CYP3A4HPGD
SCHEMBL27774626 0.88 TSHR (0.34) TSHRALDH1A1CYP3A4HPGD
SCHEMBL2124922 0.83 TSHR (0.32) TSHRALDH1A1TP53CYP3A4MAPK1
SCHEMBL2830959 0.83 TSHR (0.40) TSHRALDH1A1TP53CYP3A4HIF1A
SCHEMBL28641397 0.81 TSHR (0.38) TSHRALDH1A1TP53HIF1AHPGD
SCHEMBL1850147 0.81 TSHR (0.32) TSHRALDH1A1TP53CYP3A4MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3842417-B1 COMPOSITION, PRODUCTION METHOD FOR COMPOSITION, AND PRODUCTION METHOD FOR UNSATURATED COMPOUND RESONAC CORP (JP) 2024-01-24 EP disclosed
US-11661474-B2 Composition, production method for composition, and production method for unsaturated compound SHOWA DENKO K.K. (JP) 2023-05-30 US disclosed
CN-111836867-B Adhesive composition 株式会社LG化学 2022-09-30 CN disclosed
CN-114685713-A Polymer, electrolyte, and lithium ion battery comprising same 财团法人工业技术研究院 2022-07-01 CN disclosed
CN-111433306-B Back grinding belt 株式会社LG化学 2022-05-10 CN disclosed
CN-111655811-B Adhesive sheet for temporary attachment and method of manufacturing semiconductor device using the same 株式会社LG化学 2022-04-15 CN disclosed
CN-110785469-B Dicing die bonding film 株式会社LG化学 2022-04-08 CN disclosed
CN-108886841-B Heating element 株式会社LG化学 2022-02-25 CN disclosed
CN-111225963-B Adhesive sheet for temporary fixation and method for manufacturing semiconductor device using the same 株式会社LG化学 2022-02-22 CN disclosed
EP-3533813-B1 GEL POLYMER ELECTROLYTE, METHOD FOR PRODUCING GEL POLYMER ELECTROLYTE AND ELECTROCHROMIC DEVICE CONTAINING SAME LG CHEMICAL LTD (KR) 2022-02-09 EP disclosed
US-20120205234-A1 POLYMERIZABLE MONOMER COMPOSITION AND METHOD FOR PREVENTING POLYMERIZATION SHOWA DENKO K.K. (JP) 2012-08-16 US disclosed
US-20110137066-A1 PROCESS OF INHIBITING POLYMERIZATION OF ISOCYANATE GROUP-CONTAINING, ETHYLENICALLY UNSATURATED CARBOXYLATE COMPOUNDS, AND PROCESS FOR PRODUCING THE COMPOUNDS SHOWA DENKO K.K. (JP) 2011-06-09 US disclosed
EP-2325166-A1 METHOD FOR INHIBITING POLYMERIZATION OF ETHYLENICALLY UNSATURATED CARBOXYLIC ACID ESTER COMPOUND CONTAINING ISOCYANATE GROUP AND METHOD FOR PRODUCING ETHYLENICALLY UNSATURATED CARBOXYLIC ACID ESTER COMPOUND CONTAINING ISOCYANATE GROUP Showa Denko K.K. (JP) 2011-05-25 EP disclosed
US-20100099827-A1 POLYMERIZABLE MONOMER COMPOSITION AND METHOD FOR PREVENTING POLYMERIZATION SHOWA DENKO K.K. (JP) 2010-04-22 US disclosed
EP-2091994-A1 POLYMERIZABLE MONOMER COMPOSITION AND METHOD FOR PREVENTING POLYMERIZATION Showa Denko K.K. (JP) 2009-08-26 EP disclosed
WO-2008069256-A1 POLYMERIZABLE MONOMER COMPOSITION AND METHOD FOR PREVENTING POLYMERIZATION SHOWA DENKO K.K. (JP) 2008-06-12 WO disclosed
EP-1713787-A2 (METH) ACRYLOYL GROUP-CONTAINING OXETANE COMPOUND AND PRODUCTION METHOD THEREOF SHOWA DENKO KABUSHIKI KAISHA (JP) 2006-10-25 EP disclosed
WO-2005075445-A2 (METH) ACRYLOYL GROUP-CONTAINING OXETANE COMPOUND AND PRODUCTION METHOD THEREOF SHOWA DENKO K.K. (JP) 2005-08-18 WO disclosed
EP-0586268-B1 A pathogenic substance removing material and a blood filter comprising said material TERUMO CORP (JP) 2000-02-23 EP disclosed
EP-0586268-A1 A pathogenic substance removing material and a blood filter comprising said material TERUMO KABUSHIKI KAISHA (JP) 1994-03-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11661474-B2 Composition, production method for composition, and production method for unsaturated compound ELOVL1, ACOX1, NCOA1 TSHR 3345/4885ALDH1A1 1279/4885TP53 4827/4885
US-20110137066-A1 PROCESS OF INHIBITING POLYMERIZATION OF ISOCYANATE GROUP-CONTAINING, ETHYLENICALLY UNSATURATED CARBOXYLATE COMPOUNDS, AND PROCESS FOR PRODUCING THE COMPOUNDS ALKBH3, OGDH, IDH2 TSHR 4884/4885ALDH1A1 189/4885TP53 4083/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.