Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 10/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.53 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2126948 | 0.78 | CHRNA7 (0.52) | CHRNA7 | |
| SCHEMBL2126814 | 0.71 | CYP1A2 (0.50) | — | |
| SCHEMBL3190613 | 0.68 | CHRNA7 (0.67) | CHRNA7KCNH2KDM1A | |
| SCHEMBL3778633 | 0.67 | NPC1 (0.44) | CHRNA7 | |
| SCHEMBL17004229 | 0.65 | CHRNA7 (0.48) | CHRNA7KCNH2KDM1ASLC6A2SLC6A4 | |
| SCHEMBL20473669 | 0.64 | CHRNB2 (0.66) | CHRNA7 | |
| SCHEMBL15441312 | 0.64 | CHRNB2 (0.66) | CHRNA7 | |
| SCHEMBL4313562 | 0.64 | SLC6A4 (0.69) | CHRNA7KCNH2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2126338 | 0.63 | CHRNA7 (0.46) | CHRNA7 | |
| SCHEMBL745700 | 0.63 | CHRNA7 (0.52) | CHRNA7KCNH2KDM1ASLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2443122-A1 | DIAZAHOMOADAMANTANE DERIVATIVES AND METHODS OF USE THEREOF | Abbott Laboratories (US) | 2012-04-25 | — | — | EP | disclosed |
| WO-2010145208-A1 | DIAZAHOMOADAMANTANE DERIVATIVES AND METHODS OF USE THEREOF | ABBOTT LABORATORIES (US) | 2010-12-23 | — | — | WO | disclosed |