Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | TYK2 | P29597 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25516100 | 0.80 | MDM2 (0.47) | MDM2KDM4EL3MBTL1TAAR1EPHX1 | |
| SCHEMBL12407894 | 0.80 | MDM2 (0.52) | MDM2KDM4EL3MBTL1TAAR1EPHX1 | |
| SCHEMBL21250146 | 0.78 | TP53 (0.49) | KDM4ERAB9AKMT2AMEN1PKM | |
| SCHEMBL23866015 | 0.72 | CTSD (0.35) | MDM2KDM4EL3MBTL1TAAR1EPHX1 | |
| SCHEMBL1343362 | 0.69 | MDM2 (0.59) | MDM2KDM4EL3MBTL1TAAR1EPHX1 | |
| SCHEMBL15131704 | 0.69 | MDM2 (0.58) | MDM2KDM4EL3MBTL1TAAR1EPHX1 | |
| SCHEMBL25453609 | 0.69 | TAAR1 (0.39) | MDM2TAAR1RAB9AKMT2AMEN1 | |
| SCHEMBL14404748 | 0.67 | MAPT (0.56) | MDM2KDM4EL3MBTL1TAAR1EPHX1 | |
| SCHEMBL21746628 | 0.66 | MDM2 (0.40) | MDM2KDM4EL3MBTL1TAAR1EPHX1 | |
| SCHEMBL48610 | 0.66 | TSHR (0.69) | MDM2KDM4EL3MBTL1TAAR1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10381578-B2 | Organometallic compound and organic light-emitting device including the same | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2019-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10381578-B2 | Organometallic compound and organic light-emitting device including the same | L1CAM, MSL1, CHRM1 | MDM2 678/4885KDM4E 2858/4885L3MBTL1 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.