Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | TYK2 | P29597 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12407894 | 0.80 | MDM2 (0.52) | MDM2RAB9AKDM4EL3MBTL1TAAR1 | |
| SCHEMBL21250145 | 0.80 | MDM2 (0.47) | MDM2RAB9AKDM4EL3MBTL1TAAR1 | |
| SCHEMBL18392866 | 0.79 | TGM2 (0.55) | RAB9AKDM4ETAAR1EPHX1KMT2A | |
| SCHEMBL20013084 | 0.79 | MDM2 (0.39) | MDM2RAB9AKDM4EL3MBTL1TAAR1 | |
| SCHEMBL6430031 | 0.73 | TGM2 (0.64) | MDM2RAB9AKDM4EL3MBTL1TAAR1 | |
| SCHEMBL19546741 | 0.73 | PTPN1 (0.47) | RAB9AKDM4EL3MBTL1TAAR1KMT2A | |
| SCHEMBL24319302 | 0.71 | TGM2 (0.36) | — | |
| SCHEMBL12181323 | 0.70 | MDM2 (0.54) | MDM2RAB9AKDM4EL3MBTL1TAAR1 | |
| SCHEMBL1343362 | 0.69 | MDM2 (0.59) | MDM2RAB9AKDM4EL3MBTL1TAAR1 | |
| SCHEMBL21250127 | 0.69 | MDM2 (0.40) | MDM2KDM4EL3MBTL1TAAR1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081854-A1 | AKT3 MODULATORS | GEORGIAMUNE LLC (US) | 2023-05-11 | — | — | WO | disclosed |