Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CDC7 | O00311 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | CDK9 | P50750 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18380996 | 0.87 | ENPP3 (0.32) | — | |
| SCHEMBL25802928 | 0.87 | ENPP3 (0.32) | — | |
| SCHEMBL21251023 | 0.82 | KDM4E (0.32) | — | |
| SCHEMBL1749021 | 0.72 | PTGDR2 (0.44) | POLBKMT2A | |
| SCHEMBL17918597 | 0.71 | POLB (0.33) | POLBKMT2ACDC7PIM1CDK9 | |
| SCHEMBL2043856 | 0.70 | PIM1 (0.46) | KMT2ACDC7PIM1CDK9 | |
| SCHEMBL21490844 | 0.64 | PTGDR2 (0.46) | POLBKMT2A | |
| SCHEMBL31240613 | 0.63 | CDC7 (0.33) | CDC7PIM1CDK9 | |
| SCHEMBL2039524 | 0.63 | CDC7 (0.33) | CDC7PIM1CDK9 | |
| SCHEMBL12133625 | 0.62 | CDC7 (0.47) | POLBKMT2ACDC7PIM1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3042903-B1 | Substituted hetero-bicyclic compounds, compositions and medicinal applications thereof | IMPETIS BIOSCIENCES LTD (IN) | 2019-08-14 | — | — | EP | disclosed |