Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP3 | O14638 | 2/20 | 0.32 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.32 |
| ▸ | AXL | P30530 | 1/20 | 0.30 |
| ▸ | PRKCI | P41743 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18380996 | 1.00 | ENPP3 (0.32) | ENPP3ENPP1AXLPRKCI | |
| SCHEMBL21251024 | 0.87 | POLB (0.32) | — | |
| SCHEMBL18380981 | 0.81 | PDE4A (0.35) | — | |
| SCHEMBL14520640 | 0.73 | ENPP3 (0.41) | ENPP3ENPP1 | |
| SCHEMBL15586643 | 0.69 | ENPP3 (0.33) | ENPP3ENPP1 | |
| SCHEMBL21251023 | 0.68 | KDM4E (0.32) | — | |
| SCHEMBL2043856 | 0.68 | PIM1 (0.46) | ENPP3ENPP1AXLPRKCI | |
| SCHEMBL30751165 | 0.68 | ENPP3 (0.44) | ENPP3ENPP1 | |
| SCHEMBL5661951 | 0.68 | ENPP3 (0.44) | ENPP3ENPP1 | |
| SCHEMBL5663011 | 0.66 | PTGDR2 (0.39) | ENPP3ENPP1AXLPRKCI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3152210-B1 | TANK-BINDING KINASE INHIBITOR COMPOUNDS | GILEAD SCIENCES INC (US) | 2023-07-05 | — | — | EP | disclosed |