Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 4/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 11/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 8/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 8/20 | 0.34 |
| ▸ | NEK2 | P51955 | 4/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20331964 | 0.95 | PDE10A (0.36) | TTKPDE10APDE3BPDE3ANEK2 | |
| SCHEMBL29578107 | 0.95 | PDE10A (0.36) | TTKPDE10APDE3BPDE3ANEK2 | |
| SCHEMBL29578336 | 0.90 | TTK (0.37) | TTKPDE10APDE3BPDE3ATP53 | |
| SCHEMBL21240312 | 0.90 | TTK (0.37) | TTKPDE10APDE3BPDE3ATP53 | |
| SCHEMBL21240243 | 0.89 | TTK (0.38) | TTKPDE10APDE3BPDE3ANEK2 | |
| SCHEMBL29578389 | 0.89 | TTK (0.38) | TTKPDE10APDE3BPDE3ANEK2 | |
| SCHEMBL21251732 | 0.89 | TTK (0.36) | TTK | |
| SCHEMBL20331980 | 0.87 | TTK (0.37) | TTK | |
| SCHEMBL20331104 | 0.87 | TTK (0.36) | TTKPDE3BTP53 | |
| SCHEMBL29577692 | 0.87 | TTK (0.36) | TTKPDE3BTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3524603-A1 | FGFR4 INHIBITOR, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF | Abbisko Therapeutics Co., Ltd. (CN) | 2019-08-14 | — | — | EP | disclosed |