Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 9/20 | 0.49 |
| ▸ | FGFR2 | P21802 | 8/20 | 0.49 |
| ▸ | FGFR4 | P22455 | 8/20 | 0.49 |
| ▸ | FGFR3 | P22607 | 8/20 | 0.49 |
| ▸ | KDR | P35968 | 7/20 | 0.49 |
| ▸ | PGK1 | P00558 | 2/20 | 0.42 |
| ▸ | FLT1 | P17948 | 5/20 | 0.41 |
| ▸ | FLT4 | P35916 | 5/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21240105 | 0.87 | FGFR4 (0.43) | FGFR1FGFR2FGFR4FGFR3KDR | |
| SCHEMBL29578853 | 0.87 | FGFR4 (0.43) | FGFR1FGFR2FGFR4FGFR3KDR | |
| SCHEMBL20330753 | 0.82 | PGK1 (0.46) | FGFR1FGFR2FGFR3KDRPGK1 | |
| SCHEMBL20331085 | 0.82 | PGK1 (0.45) | FGFR1FGFR2FGFR4FGFR3KDR | |
| SCHEMBL21251983 | 0.80 | PGK1 (0.43) | FGFR1PGK1TLR9LMNACYP1A2 | |
| SCHEMBL20331048 | 0.79 | FGFR1 (0.41) | FGFR1FGFR2FGFR4FGFR3KDR | |
| SCHEMBL21251985 | 0.78 | PGK1 (0.41) | FGFR1KDRPGK1TLR9LMNA | |
| SCHEMBL21321086 | 0.75 | FGFR2 (0.42) | FGFR1FGFR2FGFR4FGFR3KDR | |
| SCHEMBL21240387 | 0.74 | FGFR4 (0.56) | FGFR1FGFR2FGFR4FGFR3KDR | |
| SCHEMBL29577775 | 0.74 | FGFR4 (0.56) | FGFR1FGFR2FGFR4FGFR3KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3524603-A1 | FGFR4 INHIBITOR, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF | Abbisko Therapeutics Co., Ltd. (CN) | 2019-08-14 | — | — | EP | disclosed |