Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 2/20 | 0.54 |
| ▸ | ACE | P12821 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | GLS | O94925 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.45 |
| ▸ | MBTPS1 | Q14703 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30910805 | 0.88 | ACE (0.50) | CASP1ACEPOLBALDH1A1RAB9A | |
| SCHEMBL18812968 | 0.86 | CASP1 (0.50) | CASP1ACEALDH1A1GLSHDAC2 | |
| SCHEMBL11940461 | 0.85 | POLB (0.51) | CASP1ACEPOLBALDH1A1RAB9A | |
| SCHEMBL28252941 | 0.85 | EPHX2 (0.50) | ACE | |
| SCHEMBL28252940 | 0.85 | EPHX2 (0.50) | ACE | |
| SCHEMBL13673884 | 0.85 | ACE (0.67) | CASP1ACEPOLBALDH1A1HDAC8 | |
| SCHEMBL4152421 | 0.85 | ACE (0.67) | CASP1ACEPOLBALDH1A1HDAC8 | |
| SCHEMBL16908006 | 0.85 | HDAC2 (0.51) | ALDH1A1RAB9AHDAC2HDAC8HDAC6 | |
| SCHEMBL28680572 | 0.85 | ALDH1A1 (0.58) | ACEALDH1A1RAB9AHDAC2HDAC8 | |
| SCHEMBL5272643 | 0.85 | ALDH1A1 (0.58) | ACEALDH1A1RAB9AHDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3092244-B1 | DIPEPTIDES AS INHIBITORS OF HUMAN IMMUNOPROTEASOMES | UNIV CORNELL (US) | 2019-08-14 | — | — | EP | disclosed |