Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MC4R | P32245 | 8/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3951751 | 0.89 | KMT2A (0.51) | KMT2ACYP1A2CYP2C9CYP2C19HPGD | |
| SCHEMBL652141 | 0.85 | GPR84 (0.64) | GPR84KMT2ASIGMAR1CYP1A2CYP2C9 | |
| SCHEMBL5830948 | 0.83 | GPR84 (0.59) | GPR84SIGMAR1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL2303485 | 0.83 | GPR84 (0.54) | GPR84MC4RSIGMAR1CYP1A2CYP2C9 | |
| SCHEMBL4948339 | 0.82 | GPR84 (0.59) | GPR84KMT2ASIGMAR1CYP1A2CYP2C9 | |
| SCHEMBL8935957 | 0.80 | GPR84 (0.58) | GPR84KMT2ASIGMAR1CYP1A2CYP2C9 | |
| SCHEMBL9301480 | 0.80 | GPR84 (0.58) | GPR84KMT2ASIGMAR1CYP1A2CYP2C9 | |
| SCHEMBL9800436 | 0.79 | CYP1A2 (0.58) | GPR84SIGMAR1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL12058584 | 0.76 | CYP1A2 (0.50) | GPR84SIGMAR1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6981704 | 0.75 | HTR2A (0.60) | KMT2ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3092244-B1 | DIPEPTIDES AS INHIBITORS OF HUMAN IMMUNOPROTEASOMES | UNIV CORNELL (US) | 2019-08-14 | — | — | EP | disclosed |