Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.50 |
| ▸ | BID | P55957 | 1/20 | 0.50 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.50 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8935957 | 1.00 | GPR84 (0.58) | GPR84SIGMAR1MCL1BIDBCL2L1 | |
| SCHEMBL4948339 | 0.98 | GPR84 (0.59) | GPR84SIGMAR1MCL1BIDBCL2L1 | |
| SCHEMBL652141 | 0.94 | GPR84 (0.64) | GPR84SIGMAR1MCL1CYP1A2CYP2C9 | |
| SCHEMBL9800436 | 0.88 | CYP1A2 (0.58) | GPR84SIGMAR1MCL1CYP1A2CYP2C9 | |
| SCHEMBL10446312 | 0.86 | SIGMAR1 (0.47) | GPR84SIGMAR1MCL1BIDBCL2L1 | |
| SCHEMBL1826164 | 0.86 | CYP1A2 (0.52) | GPR84SIGMAR1MCL1CYP1A2CYP2C9 | |
| SCHEMBL5830948 | 0.83 | GPR84 (0.59) | GPR84SIGMAR1MCL1CYP1A2CYP2C9 | |
| SCHEMBL130648 | 0.81 | SLC6A4 (0.50) | GPR84SIGMAR1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6679058 | 0.81 | CYP1A2 (0.47) | GPR84SIGMAR1MCL1CYP1A2CYP2C9 | |
| SCHEMBL130639 | 0.81 | CYP1A2 (0.47) | GPR84SIGMAR1MCL1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5354768-A | Use of imidazopyrazole derivatives as analgesics and anti-inflammatory agents | SANKYO COMPANY, LIMITED (JP) | 1994-10-11 | — | — | US | disclosed |