Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 9/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21254913 | 1.00 | RAB9A (0.40) | RAB9ANPC1SMN1; SMN2TP53MAPK1 | |
| SCHEMBL21254666 | 0.86 | MAPT (0.40) | RAB9ANPC1SMN1; SMN2TP53MAPK1 | |
| SCHEMBL21254465 | 0.85 | RAB9A (0.40) | RAB9ANPC1SMN1; SMN2TP53MAPK1 | |
| SCHEMBL21254918 | 0.83 | MAPT (0.40) | RAB9ANPC1SMN1; SMN2TP53MAPK1 | |
| SCHEMBL21254472 | 0.82 | RAB9A (0.47) | RAB9ANPC1SMN1; SMN2TP53MAPK1 | |
| SCHEMBL6120725 | 0.82 | RAB9A (0.51) | RAB9ANPC1SMN1; SMN2TP53MAPK1 | |
| SCHEMBL21254675 | 0.81 | SLC2A1 (0.47) | RAB9ANPC1SMN1; SMN2TP53MAPK1 | |
| SCHEMBL1665841 | 0.80 | RAB9A (0.47) | RAB9ANPC1SMN1; SMN2TP53MAPK1 | |
| SCHEMBL1664630 | 0.80 | RAB9A (0.47) | RAB9ANPC1SMN1; SMN2TP53MAPK1 | |
| SCHEMBL1664366 | 0.80 | HPGDS (0.54) | RAB9ANPC1SMN1; SMN2TP53MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2488486-B1 | HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES | LIGAND PHARM INC (US) | 2019-08-14 | — | — | EP | disclosed |