Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.55 |
| ▸ | NPC1 | O15118 | 7/20 | 0.55 |
| ▸ | MAPT | P10636 | 7/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8769706 | 0.94 | RAB9A (0.58) | RAB9ANPC1MAPTKMT2ALMNA | |
| SCHEMBL18745976 | 0.88 | KMT2A (0.55) | RAB9ANPC1MAPTKMT2ALMNA | |
| SCHEMBL1664311 | 0.88 | KMT2A (0.55) | RAB9ANPC1MAPTKMT2ALMNA | |
| SCHEMBL21254884 | 0.87 | RAB9A (0.52) | RAB9ANPC1MAPTKMT2ALMNA | |
| SCHEMBL1663619 | 0.87 | RAB9A (0.52) | RAB9ANPC1MAPTKMT2ALMNA | |
| SCHEMBL8770684 | 0.86 | KMT2A (0.52) | RAB9ANPC1MAPTKMT2ALMNA | |
| SCHEMBL1663107 | 0.86 | SMYD3 (0.55) | RAB9ANPC1MAPTKMT2ALMNA | |
| SCHEMBL1663377 | 0.86 | HPGDS (0.55) | RAB9ANPC1MAPTKMT2ALMNA | |
| SCHEMBL21254900 | 0.86 | MAPT (0.45) | RAB9ANPC1MAPTKMT2ALMNA | |
| SCHEMBL1664469 | 0.85 | RAB9A (0.58) | RAB9ANPC1MAPTKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2488486-B1 | HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES | LIGAND PHARM INC (US) | 2019-08-14 | — | — | EP | disclosed |