Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 11/20 | 0.62 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.53 |
| ▸ | NT5E | P21589 | 2/20 | 0.51 |
| ▸ | P2RY11 | Q96G91 | 2/20 | 0.47 |
| ▸ | PNP | P00491 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21100457 | 0.92 | P2RY1 (0.65) | P2RY1P2RY2NT5EP2RY11PNP | |
| SCHEMBL21100284 | 0.84 | ADORA3 (0.57) | P2RY1PNPLMNATP53HTT | |
| SCHEMBL16258261 | 0.84 | P2RY1 (0.66) | P2RY1P2RY2NT5EP2RY11ADORA3 | |
| SCHEMBL21100587 | 0.83 | P2RY1 (0.53) | P2RY1P2RY2NT5EP2RY11 | |
| SCHEMBL21100303 | 0.81 | P2RY1 (0.52) | P2RY1P2RY2NT5EP2RY11 | |
| Phosphoric Acid SCHEMBL21050274 | 0.80 | P2RY1 (0.49) | P2RY1P2RY2NT5EADORA3HSP90AA1 | |
| Phosphoric Acid SCHEMBL21050227 | 0.80 | P2RY1 (0.49) | P2RY1P2RY2NT5EADORA3HSP90AA1 | |
| SCHEMBL21050273 | 0.78 | P2RY1 (0.62) | P2RY1P2RY2NT5EP2RY11HSP90AA1 | |
| SCHEMBL21050226 | 0.78 | P2RY1 (0.62) | P2RY1P2RY2NT5EP2RY11HSP90AA1 | |
| SCHEMBL19503300 | 0.78 | P2RY1 (0.67) | P2RY1P2RY2NT5EP2RY11ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019157317-A1 | COMPOUNDS AND METHODS FOR TREATING ADDICTION AND RELATED DISORDERS | ASTROCYTE PHARMACEUTICALS, INC. (US) | 2019-08-15 | — | — | WO | disclosed |