Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBNL1 | Q9NR56 | 1/20 | 1.00 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 6/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29985784 | 0.82 | MBNL1 (0.70) | MBNL1PDE10ATDP1ADORA2ANPC1 | |
| SCHEMBL22326435 | 0.81 | PDE10A (0.77) | MBNL1PDE10ATDP1NPC1RAB9A | |
| SCHEMBL30462943 | 0.79 | MBNL1 (0.66) | MBNL1PDE10AADORA2ANPC1RAB9A | |
| SCHEMBL17363620 | 0.77 | MBNL1 (0.61) | MBNL1ADORA2ANPC1RAB9AMAPT | |
| SCHEMBL27993150 | 0.77 | MBNL1 (0.62) | MBNL1PDE10ATDP1ADORA2ANPC1 | |
| SCHEMBL28085639 | 0.76 | PDE10A (0.74) | MBNL1PDE10ATDP1ADORA2AMAPT | |
| SCHEMBL8956231 | 0.76 | MBNL1 (0.60) | MBNL1ADORA2ANPC1RAB9AMAPT | |
| SCHEMBL29942008 | 0.75 | DHODH (0.62) | MBNL1PDE10ABACE1DHODH | |
| SCHEMBL8732571 | 0.75 | DHODH (0.62) | MBNL1PDE10ABACE1DHODH | |
| SCHEMBL2125225 | 0.74 | PDE10A (1.00) | MBNL1PDE10ATDP1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112521333-A | Synthesis method of chiral 2, 3-disubstituted tetrahydroquinoline derivative | 中国科学院大连化学物理研究所 | 2021-03-19 | — | — | CN | disclosed |
| US-20120094972-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USES | AMGEN INC. (US) | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120094972-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USES | MCL1, MALT1, BCL9 | MBNL1 1806/4885PDE10A 3392/4885TDP1 2061/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.