Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 13/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SIRT6 | Q8N6T7 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6328932 | 0.99 | HPGD (0.49) | HPGDMAPTMAPK1ALDH1A1CYP1A2 | |
| SCHEMBL6321576 | 0.95 | HPGD (0.46) | HPGDMAPTMAPK1ALDH1A1CYP1A2 | |
| SCHEMBL2128163 | 0.83 | MEN1 (0.45) | MAPTMAPK1ALDH1A1CYP2C19CYP2C9 | |
| Hydrochloric Acid SCHEMBL6323525 | 0.82 | MEN1 (0.44) | MAPTMAPK1ALDH1A1CYP2C19CYP2C9 | |
| SCHEMBL2127393 | 0.81 | RAD52 (0.41) | MAPTMAPK1HTTGAACYP3A4 | |
| Hydrochloric Acid SCHEMBL2540311 | 0.80 | RAD52 (0.40) | MAPTGAACYP3A4 | |
| Hydrochloric Acid SCHEMBL6328982 | 0.79 | RAD52 (0.40) | MAPTGAACYP3A4 | |
| SCHEMBL6331162 | 0.79 | MEN1 (0.44) | MAPTMAPK1ALDH1A1SIRT6LMNA | |
| SCHEMBL6158539 | 0.79 | MEN1 (0.44) | MAPTMAPK1ALDH1A1SIRT6LMNA | |
| SCHEMBL27913615 | 0.78 | HPGD (0.65) | HPGDMAPTMAPK1ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1348695-B1 | Derivatives of paraphenylene diamine with pyrrolidine groups substituted by cationic radicals and their use for dyeing keratinic fibre | OREAL (FR) | 2012-04-25 | — | — | EP | disclosed |
| EP-1348695-A1 | Derivatives of paraphenylene diamine with pyrrolidine groups substituted by cationic radicals and their use for dyeing keratinic fibre | L'OREAL (FR) | 2003-10-01 | — | — | EP | disclosed |