Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 8/20 | 0.44 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6323525 | 0.99 | MEN1 (0.44) | MEN1KMT2AMAPTSIRT6ALDH1A1 | |
| SCHEMBL6331162 | 0.94 | MEN1 (0.44) | MEN1KMT2AMAPTSIRT6ALDH1A1 | |
| SCHEMBL6158539 | 0.94 | MEN1 (0.44) | MEN1KMT2AMAPTSIRT6ALDH1A1 | |
| SCHEMBL2126038 | 0.83 | HPGD (0.50) | KMT2AMAPTSIRT6ALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL6328932 | 0.82 | HPGD (0.49) | KMT2AMAPTSIRT6ALDH1A1MAPK1 | |
| SCHEMBL2126499 | 0.81 | MAPT (0.37) | MEN1KMT2AMAPTALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL2537577 | 0.80 | MAPT (0.36) | MEN1KMT2AMAPTALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL6331452 | 0.80 | MAPT (0.36) | MEN1KMT2AMAPTALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL6159442 | 0.80 | MAPT (0.37) | MEN1KMT2AMAPTALDH1A1MAPK1 | |
| SCHEMBL6321576 | 0.79 | HPGD (0.46) | KMT2AMAPTSIRT6ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1348695-B1 | Derivatives of paraphenylene diamine with pyrrolidine groups substituted by cationic radicals and their use for dyeing keratinic fibre | OREAL (FR) | 2012-04-25 | — | — | EP | disclosed |
| EP-1348695-A1 | Derivatives of paraphenylene diamine with pyrrolidine groups substituted by cationic radicals and their use for dyeing keratinic fibre | L'OREAL (FR) | 2003-10-01 | — | — | EP | disclosed |