Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 11/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22681145 | 0.87 | RAB7A (0.37) | GLO1MAPTHPGDSMN1; SMN2LMNA | |
| SCHEMBL21247134 | 0.84 | GLO1 (0.64) | GLO1MAPTHPGDSMN1; SMN2RAB9A | |
| SCHEMBL21260702 | 0.82 | GLO1 (0.67) | GLO1MAPTHPGDSMN1; SMN2RAB9A | |
| SCHEMBL22680805 | 0.78 | ACACB (0.33) | MAPTHPGDSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL22696752 | 0.76 | GLO1 (0.48) | GLO1MAPTHPGDSMN1; SMN2RAB9A | |
| SCHEMBL21259190 | 0.75 | ACACB (0.33) | — | |
| SCHEMBL21247309 | 0.72 | GLO1 (0.50) | GLO1MAPTHPGDSMN1; SMN2RAB9A | |
| SCHEMBL21247394 | 0.71 | RAB7A (0.56) | GLO1MAPTHPGDSMN1; SMN2RAB9A | |
| SCHEMBL22696625 | 0.71 | MEN1 (0.64) | MAPTHPGDSMN1; SMN2RAB9ALMNA | |
| SCHEMBL22696614 | 0.70 | CXCR2 (0.48) | MAPTLMNAPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019154949-A1 | FUSED THIOPHENE DERIVATIVES AND THEIR USES | ENYO PHARMA (FR) | 2019-08-15 | — | — | WO | disclosed |