Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.42 |
| ▸ | MEN1 | O00255 | 7/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 4/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 4/20 | 0.39 |
| ▸ | RAB7A | P51149 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21247296 | 0.91 | PTPN1 (0.53) | PTPN1KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL21261036 | 0.89 | PTPN1 (0.55) | PTPN1KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL21247442 | 0.89 | PTPN1 (0.55) | PTPN1KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL21247169 | 0.87 | PTPN1 (0.53) | PTPN1KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL21250179 | 0.86 | PTPN1 (0.53) | PTPN1KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL21247306 | 0.85 | PTPN1 (0.52) | PTPN1KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL22681000 | 0.85 | PTPN1 (0.48) | PTPN1 | |
| SCHEMBL21247294 | 0.85 | PTPN1 (0.51) | PTPN1KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL21247337 | 0.83 | PTPN1 (0.68) | PTPN1KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL21247234 | 0.82 | PTPN1 (0.64) | PTPN1KMT2AMEN1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200361924-A1 | FUSED THIOPHENE DERIVATIVES AND THEIR USES | ENYO PHARMA (FR) | 2020-11-19 | — | — | US | disclosed |
| WO-2019154950-A1 | FUSED THIOPHENE DERIVATIVES AND THEIR USES | ENYO PHARMA (FR) | 2019-08-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200361924-A1 | FUSED THIOPHENE DERIVATIVES AND THEIR USES | FTH1, SLC40A1, FECH | PTPN1 1639/4885KMT2A 3454/4885MEN1 3538/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.