Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM4 | O15151 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CETP | P11597 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21253061 | 0.88 | MAPK1 (0.35) | MDM4TP53GAACETPLMNA | |
| SCHEMBL21261301 | 0.81 | ALDH1A1 (0.48) | LMNAL3MBTL1ALDH1A1HTTNPSR1 | |
| SCHEMBL21261480 | 0.79 | SCN1A (0.56) | GAALMNAALDH1A1HPGDKDM4E | |
| SCHEMBL23662229 | 0.76 | KDM4E (0.41) | GAALMNAALDH1A1SMN1; SMN2HTT | |
| SCHEMBL29414711 | 0.76 | L3MBTL1 (0.46) | TP53CETPLMNAL3MBTL1ADORA1 | |
| SCHEMBL22632771 | 0.76 | L3MBTL1 (0.46) | TP53CETPLMNAL3MBTL1ADORA1 | |
| SCHEMBL21247092 | 0.74 | ALDH1A1 (0.43) | ALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL21247091 | 0.74 | ALDH1A1 (0.43) | ALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL31696362 | 0.74 | KMT2A (0.35) | GAALMNAL3MBTL1ALDH1A1HPGD | |
| SCHEMBL25247132 | 0.74 | KMT2A (0.35) | GAALMNAL3MBTL1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019154329-A1 | COMPOUND HAVING BET INHIBITORY ACTIVITY AND PREPARATION METHOD AND USE THEREFOR | 上海海和药物研究开发有限公司 | 2019-08-15 | — | — | WO | disclosed |