Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.37 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.37 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27910392 | 0.82 | NPC1 (0.43) | ALDH1A1NPC1PPARGPPARASMN1; SMN2 | |
| SCHEMBL28806458 | 0.82 | PPARG (0.47) | ALDH1A1NPC1PPARGPPARASMN1; SMN2 | |
| SCHEMBL8446184 | 0.76 | ALDH1A1 (0.50) | ALDH1A1NPC1RAB9AKMT2AKCNJ6 | |
| SCHEMBL27644397 | 0.75 | PPARG (0.41) | ALDH1A1NPC1PPARGPPARASMN1; SMN2 | |
| SCHEMBL14862584 | 0.74 | SLC6A2 (0.47) | ALDH1A1NPC1PPARGPPARASMN1; SMN2 | |
| SCHEMBL27555743 | 0.73 | PPARG (0.48) | ALDH1A1NPC1PPARGPPARASMN1; SMN2 | |
| SCHEMBL2125408 | 0.73 | SLC6A2 (0.40) | ALDH1A1NPC1PPARGPPARASMN1; SMN2 | |
| SCHEMBL8224139 | 0.72 | SLC6A2 (0.48) | ALDH1A1PPARGPPARASMN1; SMN2SLC6A2 | |
| SCHEMBL1454624 | 0.71 | NPC1 (0.46) | ALDH1A1NPC1PPARGPPARASMN1; SMN2 | |
| SCHEMBL14208222 | 0.71 | PPARG (0.53) | ALDH1A1NPC1PPARGPPARASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120108422-A1 | Antifungal 1,2,4-triazolyl Derivatives | BASF SE (DE) | 2012-05-03 | — | — | US | disclosed |
| EP-2443097-A1 | ANTIFUNGAL 1, 2, 4-TRIAZOLYL DERIVATIVES | BASF SE (DE) | 2012-04-25 | — | — | EP | disclosed |
| WO-2010146111-A1 | ANTIFUNGAL 1, 2, 4-TRIAZOLYL DERIVATIVES | BASF SE (DE) | 2010-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120108422-A1 | Antifungal 1,2,4-triazolyl Derivatives | ERG28, CYP51A1, DPM1 | ALDH1A1 1943/4885NPC1 1947/4885PPARG 3932/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.