SCHEMBL2126258

SCHEMBL2126258

O=C1C(=O)C(Cl)C(=O)c2ccccc21

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S100A4 P26447 5/20 0.58
MEN1 O00255 5/20 0.50
KMT2A Q03164 5/20 0.50
CDC25B P30305 3/20 0.50
DNMT1 P26358 2/20 0.48
IDO1 P14902 1/20 0.48
DNMT3L Q9UJW3 1/20 0.48
DNMT3A Q9Y6K1 1/20 0.48
MAPT P10636 4/20 0.48
POLB P06746 3/20 0.48
LMNA P02545 3/20 0.48
RAB9A P51151 3/20 0.48
MAPK1 P28482 2/20 0.48
APAF1 O14727 2/20 0.48
TDP2 O95551 2/20 0.48
KDM4E B2RXH2 2/20 0.48
BLM P54132 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
THRB P10828 2/20 0.48
MAOA P21397 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11595145 0.90 S100A4 (0.70) S100A4MEN1KMT2ACDC25BDNMT1
Sulfuric Acid SCHEMBL29267238 0.90 S100A4 (0.48) S100A4MEN1KMT2ACDC25BDNMT1
Sulfuric Acid SCHEMBL30989355 0.90 S100A4 (0.48) S100A4MEN1KMT2ACDC25BDNMT1
Sulfuric Acid SCHEMBL989868 0.90 S100A4 (0.48) S100A4MEN1KMT2ACDC25BDNMT1
SCHEMBL29006544 0.79 S100A4 (0.50) S100A4MEN1KMT2ACDC25BDNMT1
SCHEMBL7597246 0.76 S100A4 (0.47) S100A4MEN1KMT2ACDC25BDNMT1
SCHEMBL2599340 0.74 S100A4 (1.00) S100A4MEN1KMT2ACDC25BDNMT1
SCHEMBL31237472 0.74 S100A4 (1.00) S100A4MEN1KMT2ACDC25BDNMT1
SCHEMBL23043831 0.71 MEN1 (0.50) S100A4MEN1KMT2ACDC25BDNMT1
SCHEMBL22272424 0.71 MEN1 (0.50) S100A4MEN1KMT2ACDC25BDNMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2442643-A1 A PROCESS FOR PREPARATION OF STABLE, MICROENCAPSULATED AND SUSTAINED RELEASE BIOCIDAL ACTIVES AND COMPOSITION THEREOF Isp Investments Inc. (US) 2012-04-25 EP disclosed
WO-2010148158-A1 A PROCESS FOR PREPARATION OF STABLE, MICROENCAPSULATED AND SUSTAINED RELEASE BIOCIDAL ACTIVES AND COMPOSITION THEREOF ISP INVESTMENTS INC. (US) 2010-12-23 WO disclosed
EP-0900006-A1 EMULSIFIER FOR PESTICIDE CONCENTRATES HENKEL CORPORATION (US) 1999-03-10 EP disclosed
WO-1997040669-A1 EMULSIFIER FOR PESTICIDE CONCENTRATES HENKEL CORPORATION (US) 1997-11-06 WO disclosed
EP-0508667-B1 Aqueous agricultural compositions, methods of making them and their use MONSANTO CO (US) 1996-06-05 EP disclosed
EP-0508667-A1 Aqueous agricultural compositions, methods of making them and their use MONSANTO COMPANY (US) 1992-10-14 EP disclosed