Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 3/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.55 |
| ▸ | MEN1 | O00255 | 6/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | PIM1 | P11309 | 1/20 | 0.48 |
| ▸ | CDC25B | P30305 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.43 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.43 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31237472 | 1.00 | S100A4 (1.00) | S100A4KMT2AMEN1POLBMAPT | |
| SCHEMBL7645697 | 0.85 | S100A4 (0.73) | S100A4KMT2AMEN1POLBMAPT | |
| SCHEMBL19147624 | 0.83 | S100A4 (0.70) | S100A4KMT2AMEN1POLBMAPT | |
| SCHEMBL19130059 | 0.83 | S100A4 (0.70) | S100A4KMT2AMEN1POLBMAPT | |
| SCHEMBL11595145 | 0.82 | S100A4 (0.70) | S100A4KMT2AMEN1POLBMAPT | |
| SCHEMBL2126258 | 0.74 | S100A4 (0.58) | S100A4KMT2AMEN1POLBMAPT | |
| SCHEMBL11741033 | 0.73 | S100A4 (0.56) | S100A4KMT2AMEN1POLBKDM4E | |
| SCHEMBL9641853 | 0.72 | S100A4 (0.56) | S100A4RAB9APIM1CES1 | |
| SCHEMBL2205822 | 0.72 | S100A4 (0.56) | S100A4KMT2AMEN1POLBMAPT | |
| SCHEMBL2599235 | 0.71 | S100A4 (1.00) | S100A4KMT2AMEN1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130090355-A1 | CHEMICAL AGENTS FOR THE PREVENTION OF INHIBITION OR TUMOR METASTASIS | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2013-04-11 | — | — | US | claimed |
| WO-2011146101-A1 | CHEMICAL AGENTS FOR THE PREVENTION OR INHIBITION OF TUMOR METASTASIS | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2011-11-24 | — | — | WO | claimed |
| JP-52151155-A | — | — | None | — | — | JP | disclosed |
| US-20190022100-A1 | ANTIVIRAL COMPOUNDS AND METHODS OF USE THEREOF | TRANA DISCOVERY INC (US) | 2019-01-24 | — | — | US | disclosed |
| CN-106831379-A | A kind of method that 2,3 dichloro Isosorbide-5-Nitrae naphthoquinones are prepared with 2 chlorine Isosorbide-5-Nitrae naphthoquinones production process waste materials | 天门楚天精细化工有限公司 | 2017-06-13 | — | — | CN | disclosed |
| US-20160129006-A1 | ANTIVIRAL COMPOUNDS AND METHODS OF USE THEREOF | TRANA DISCOVERY INC (US) | 2016-05-12 | — | — | US | disclosed |
| US-20160129006-A1 | ANTIVIRAL COMPOUNDS AND METHODS OF USE THEREOF | TRANA DISCOVERY INC (US) | 2016-05-12 | — | — | US | disclosed |
| US-9173886-B2 | Antiviral compounds and methods of use thereof | TRANA DISCOVERY, INC. (US) | 2015-11-03 | — | — | US | disclosed |
| US-9173886-B2 | Antiviral compounds and methods of use thereof | TRANA DISCOVERY, INC. (US) | 2015-11-03 | — | — | US | disclosed |
| US-20130090355-A1 | CHEMICAL AGENTS FOR THE PREVENTION OF INHIBITION OR TUMOR METASTASIS | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2013-04-11 | — | — | US | disclosed |
| US-20130090355-A1 | CHEMICAL AGENTS FOR THE PREVENTION OF INHIBITION OR TUMOR METASTASIS | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2013-04-11 | — | — | US | disclosed |
| WO-2010111718-A2 | ANTIVIRAL COMPOUNDS AND METHODS OF USE THEREOF | TRANA DISCOVERY (US) | 2010-09-30 | — | — | WO | disclosed |
| WO-2005053609-A2 | METHODS OF NAD+-DEPENDENT DEACETYLASE INHIBITORS | GUILFORD PHARMACEUTICALS INC. (US) | 2005-06-16 | — | — | WO | disclosed |
| EP-0062540-B1 | PHOTOSENSITIVE COMPOSITION FOR ELECTROPHOTOGRAPHY | MITA INDUSTRIAL CO. LTD. (JP) | 1987-01-14 | — | — | EP | disclosed |
| EP-0088607-B1 | ORGANIC PHOTOSENSITIVE MATERIAL FOR ELECTROPHOTOGRAPHY | MITA INDUSTRIAL CO. LTD. (JP) | 1986-07-16 | — | — | EP | disclosed |
| US-4447514-A | PYRYLENE PIGMENT | MITA INDUSTRIAL CO., LTD. (JP) | 1984-05-08 | — | — | US | disclosed |
| US-4438187-A | POLYVINYLCARBAZOLE, AND PERYLENE PIGMENT | MITA INDUSTRIAL CO. LTD. (JP) | 1984-03-20 | — | — | US | disclosed |
| EP-0088607-A2 | Organic photosensitive material for electrophotography | MITA INDUSTRIAL CO. LTD. (JP) | 1983-09-14 | — | — | EP | disclosed |
| EP-0062540-A2 | Photosensitive composition for electrophotography | MITA INDUSTRIAL CO. LTD. (JP) | 1982-10-13 | — | — | EP | disclosed |
| JP-S52151155-A | PREPARATION OF 2,3-DIHYDRO-2,3-DICHLORO-1,4-NAPHTHOQUINONE | KAWASAKI KASEI CHEM LTD | 1977-12-15 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130090355-A1 | CHEMICAL AGENTS FOR THE PREVENTION OF INHIBITION OR TUMOR METASTASIS | S100A4, S100A6, S100A10 | S100A4 1/4885KMT2A 3613/4885MEN1 1065/4885 |
| US-20160129006-A1 | ANTIVIRAL COMPOUNDS AND METHODS OF USE THEREOF | TYMP, MAVS, ZC3HAV1 | S100A4 4404/4885KMT2A 2800/4885MEN1 4495/4885 |
| US-20190022100-A1 | ANTIVIRAL COMPOUNDS AND METHODS OF USE THEREOF | TYMP, MAVS, ZC3HAV1 | S100A4 4404/4885KMT2A 2800/4885MEN1 4495/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.