SCHEMBL21262944

SCHEMBL21262944

Cc1ccc2c(ccc3ccccc32)c1N1C=CN(C)C1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 3/20 0.42
CYP1A2 P05177 4/20 0.41
TSHR P16473 4/20 0.41
CYP2A6 P11509 3/20 0.41
ALDH1A1 P00352 4/20 0.39
LCK P06239 1/20 0.39
FYN P06241 1/20 0.39
ADORA3 P0DMS8 1/20 0.39
MAPT P10636 1/20 0.39
ACHE P22303 1/20 0.39
SLC6A2 P23975 1/20 0.39
AHR P35869 1/20 0.39
HSD17B10 Q99714 3/20 0.36
TDP1 Q9NUW8 1/20 0.36
HCAR1 Q9BXC0 3/20 0.36
HPGD P15428 2/20 0.36
CYP3A4 P08684 1/20 0.34
MAPK1 P28482 1/20 0.34
CASP1 P29466 1/20 0.34
RAB9A P51151 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21262981 0.87 TSHR (0.40) CYP1A2TSHRCYP2A6ALDH1A1LCK
SCHEMBL20752001 0.74 PGR (0.35) CYP1A2TSHRALDH1A1MAPTAHR
SCHEMBL20865196 0.74
Bromide SCHEMBL28205273 0.71 HSD17B10 (0.41) CYP1A2TSHRCYP2A6ALDH1A1MAPT
SCHEMBL20022874 0.70 KDM4E (0.40) ALDH1A1MAPTHPGDL3MBTL1CYP1A1
SCHEMBL20751999 0.67
SCHEMBL7108062 0.67 TSHR (0.78) HPRT1CYP1A2TSHRCYP2A6ALDH1A1
SCHEMBL458566 0.67 TSHR (0.78) HPRT1CYP1A2TSHRCYP2A6ALDH1A1
SCHEMBL31747510 0.67 TSHR (0.78) HPRT1CYP1A2TSHRCYP2A6ALDH1A1
Chrysene SCHEMBL27805598 0.66 HPRT1 (0.70) HPRT1CYP1A2TSHRCYP2A6ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11342509-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-05-24 US disclosed
US-20190252619-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-08-15 US disclosed