Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2125962 | 1.00 | CHRM3 (0.48) | CHRM3LMNACHRM2CHRM1CHRM4 | |
| SCHEMBL2125965 | 1.00 | CHRM3 (0.48) | CHRM3LMNACHRM2CHRM1CHRM4 | |
| SCHEMBL2126331 | 1.00 | CHRM3 (0.48) | CHRM3LMNACHRM2CHRM1CHRM4 | |
| SCHEMBL23315208 | 0.74 | LMNA (0.56) | CHRM3LMNACHRM2CHRM1CHRM4 | |
| SCHEMBL19884935 | 0.74 | LMNA (0.56) | CHRM3LMNACHRM2CHRM1CHRM4 | |
| SCHEMBL2127685 | 0.73 | CYP2B6 (0.50) | CHRM3LMNACHRM2CHRM1CHRM4 | |
| SCHEMBL2128439 | 0.73 | CYP2B6 (0.50) | CHRM3LMNACHRM2CHRM1CHRM4 | |
| SCHEMBL7445903 | 0.72 | CHRM3 (0.38) | CHRM3LMNACHRM2CHRM1CHRM4 | |
| SCHEMBL7445905 | 0.72 | CHRM3 (0.35) | CHRM3LMNACHRM2CHRM1CHRM4 | |
| SCHEMBL327106 | 0.72 | CYP2B6 (0.45) | CHRM3LMNACHRM2CHRM1CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121137-B1 | QUINUCLIDINOL DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS | ASTRAZENECA AB (SE) | 2012-04-25 | — | — | EP | disclosed |