Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | XDH | P47989 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.49 |
| ▸ | CNR2 | P34972 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA7 | P43166 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22824418 | 0.93 | KDM4E (0.65) | LMNAXDHKDM4EGAAPOLB | |
| SCHEMBL17655667 | 0.86 | KDM4E (0.57) | LMNAXDHKDM4EGAAPOLB | |
| SCHEMBL30594704 | 0.84 | KDM4E (0.77) | LMNAXDHKDM4EGAAPOLB | |
| SCHEMBL1465618 | 0.84 | KDM4E (0.77) | LMNAXDHKDM4EGAAPOLB | |
| SCHEMBL19272079 | 0.80 | LMNA (0.68) | LMNAXDHKDM4EGAAPOLB | |
| SCHEMBL22824549 | 0.79 | PTGS2 (0.83) | LMNAKDM4EPOLBFUT7TDP1 | |
| SCHEMBL29913216 | 0.79 | PTGS2 (0.83) | LMNAKDM4EPOLBFUT7TDP1 | |
| SCHEMBL24613986 | 0.79 | KDM4E (0.67) | LMNAXDHKDM4EGAAPOLB | |
| Syringate SCHEMBL159392 | 0.78 | CA12 (0.67) | LMNAXDHKDM4EGAAPOLB | |
| SCHEMBL20693295 | 0.77 | TSHR (0.48) | LMNAXDHKDM4EGAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019155169-A1 | DIFUNCTIONAL BIPHENYL COMPOUNDS, PREPARATION, AND USES | ARIANEGROUP SAS (FR) | 2019-08-15 | — | — | WO | disclosed |