SCHEMBL2126445

SCHEMBL2126445

CCCCCCCCCCCCCCCCCC(C)(C)[SiH3]

nearest known ligand 0.47

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.47
THRB P10828 1/20 0.47
GGPS1 O95749 6/20 0.41
FDPS P14324 9/20 0.39
SMPD1 P17405 2/20 0.38
CES2 O00748 1/20 0.38
LPAR1 Q92633 1/20 0.38
LPAR3 Q9UBY5 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28897317 1.00 TSHR (0.47) TSHRTHRBGGPS1FDPSSMPD1
SCHEMBL15068127 1.00 TSHR (0.47) TSHRTHRBGGPS1FDPSSMPD1
SCHEMBL6049085 1.00 TSHR (0.47) TSHRTHRBGGPS1FDPSSMPD1
SCHEMBL2723204 0.97
SCHEMBL8037927 0.88
SCHEMBL31297408 0.87 FFAR1 (0.33)
SCHEMBL31297413 0.87 FFAR1 (0.33)
SCHEMBL31297410 0.87 FFAR1 (0.33)
SCHEMBL31297412 0.87 FFAR1 (0.33)
Naphthalene SCHEMBL20979868 0.82 HTT (0.43) THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170283368-A1 METHODS FOR SYNTHESIZING SUBSTITUTED TETRACYCLINE COMPOUNDS PARATEK PHARMACEUTICALS, INC. 2017-10-05 US claimed
EP-2014797-A2 Coating composition for interconnection part of electrode and plasma display panel including the same Samsung SDI Co., Ltd. (KR) 2009-01-14 EP claimed
US-20080303439-A1 Coating composition for interconnection part of electrode and plasma display panel including the same SAMSUNG SDI CO., LTD., A CORP. OF THE REPUBLIC OF KOREA (KR) 2008-12-11 US claimed
EP-0706653-B1 SYSTEM FOR BENZODIAZEPINE DETECTION BIO RAD LABORATORIES (US) 1998-03-04 EP claimed
EP-0706653-A1 SYSTEM FOR BENZODIAZEPINE DETECTION BIO-RAD LABORATORIES, INC. (US) 1996-04-17 EP claimed
US-5416023-A System for benzodiazepine detection BIO-RAD LABORATORIES, INC. (US) 1995-05-16 US claimed
WO-1995001566-A1 SYSTEM FOR BENZODIAZEPINE DETECTION BIO-RAD LABORATORIES, INC. (US) 1995-01-12 WO claimed
US-5352585-A System for benzodiazepine detection BIO-RAD LABORATORIES, INC. (US) 1994-10-04 US claimed
US-20250340507-A1 METHODS FOR SYNTHESIZING SUBSTITUTED TETRACYCLINE COMPOUNDS PARATEK PHARM INNC (US) 2025-11-06 US disclosed
US-12422446-B2 Pretreatment method of an automatic analyzer HITACHI HIGH-TECH CORPORATION (JP) 2025-09-23 US disclosed
EP-3968029-B1 AUTOMATIC ANALYSIS DEVICE PRETREATMENT METHOD HITACHI HIGH TECH CORP (JP) 2025-05-21 EP disclosed
CN-113785204-B Pretreatment method for automatic analysis device 株式会社日立高新技术 2024-10-15 CN disclosed
US-12037357-B2 Compounds for activating invariant natural killer T-cells and methods of use in eliminating inflammatory senescent cells DECIDUOUS THERAPEUTICS, INC. (US) 2024-07-16 US disclosed
US-20240025936-A1 COMPOUNDS FOR ACTIVATING INVARIANT NATURAL KILLER T-CELLS AND METHODS OF USE IN ELIMINATING INFLAMMATORY SENESCENT CELLS DECIDUOUS THERAPEUTICS, INC. (US) 2024-01-25 US disclosed
US-5427915-A Using a crystalline anisotropic polymerized polyunsaturated lipid monolayer capable of specific binding to analyte BIOCIRCUITS CORPORATION (US) 1995-06-27 US disclosed
WO-1995001566-A1 SYSTEM FOR BENZODIAZEPINE DETECTION BIO-RAD LABORATORIES, INC. (US) 1995-01-12 WO disclosed
EP-0629443-A1 Process for preparing a metal catalyst with in situ generated carrier for the hydrogenation of organic compounds and catalyst obtained by means of such a process MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) 1994-12-21 EP disclosed
US-5268305-A Multi-optical detection system BIOCIRCUITS CORPORATION (US) 1993-12-07 US disclosed
EP-0563317-A1 MULTI-OPTICAL DETECTION SYSTEM BIOCIRCUITS CORPORATION (US) 1993-10-06 EP disclosed
WO-1992010758-A1 MULTI-OPTICAL DETECTION SYSTEM BIOCIRCUITS CORPORATION (US) 1992-06-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12037357-B2 Compounds for activating invariant natural killer T-cells and methods of use in eliminating inflammatory senescent cells IL2, IL4, PBK TSHR 3328/4885THRB 2737/4885GGPS1 1471/4885
US-20240025936-A1 COMPOUNDS FOR ACTIVATING INVARIANT NATURAL KILLER T-CELLS AND METHODS OF USE IN ELIMINATING INFLAMMATORY SENESCENT CELLS IL2, PBK, IL4 TSHR 3553/4885THRB 3093/4885GGPS1 1741/4885
US-20250340507-A1 METHODS FOR SYNTHESIZING SUBSTITUTED TETRACYCLINE COMPOUNDS TET3, TET1, DHFR TSHR 2369/4885THRB 1828/4885GGPS1 87/4885
US-20170283368-A1 METHODS FOR SYNTHESIZING SUBSTITUTED TETRACYCLINE COMPOUNDS TET3, TET1, DHFR TSHR 2369/4885THRB 1828/4885GGPS1 87/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.