Histidine

Histidine

SCHEMBL2126474

CC(C)C[C@H](N)C(=O)O.CC(C)[C@H](N)C(=O)O.C[C@@H](O)[C@H](N)C(=O)O.N[C@@H](CS)C(=O)O.N[C@@H](Cc1c[nH]cn1)C(=O)O

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 3/20 0.38
PTGS1 P23219 1/20 0.33
SLC7A11 Q9UPY5 1/20 0.33
SLC1A3 P43003 2/20 0.32
SLC1A2 P43004 2/20 0.32
CYP3A4 P08684 1/20 0.31
CYP1A2 P05177 1/20 0.30
SLC1A1 P43005 1/20 0.30
ANPEP P15144 1/20 0.30
RNPEP Q9H4A4 1/20 0.30
DNPEP Q9ULA0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Histidine SCHEMBL21638967 0.91 SLC7A5 (0.45) SLC7A5PTGS1SLC1A3SLC1A2CYP3A4
Histidine SCHEMBL245022 0.91 SLC7A5 (0.45) SLC7A5PTGS1SLC1A3SLC1A2CYP3A4
Leucine SCHEMBL2126472 0.91 SLC7A5 (0.34) SLC7A5
Histidine SCHEMBL716108 0.85 SLC7A5 (0.51) SLC7A5PTGS1SLC1A3SLC1A2CYP3A4
Histidine SCHEMBL716109 0.85 SLC7A5 (0.51) SLC7A5PTGS1SLC1A3SLC1A2CYP3A4
Histidine SCHEMBL1061774 0.85 SLC7A5 (0.43) SLC7A5PTGS1CYP3A4CYP1A2
Histidine SCHEMBL1537416 0.85 SLC7A5 (0.51) SLC7A5PTGS1SLC1A3SLC1A2CYP3A4
Histidine SCHEMBL6426901 0.85 SLC7A5 (0.40) SLC7A5PTGS1CYP3A4CYP1A2
Histidine SCHEMBL1537307 0.85 SLC7A5 (0.43) SLC7A5PTGS1CYP3A4CYP1A2
Histidine SCHEMBL1061772 0.85 SLC7A5 (0.43) SLC7A5PTGS1CYP3A4CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3447494-B1 ANALYSIS METHOD USING ANALYSIS DEVICE PHC HOLDINGS CORP (JP) 2020-07-15 EP disclosed
EP-3141901-B1 ANALYSIS DEVICE, AND ANALYSIS APPARATUS AND METHOD USING THE SAME PHC HOLDINGS CORP (JP) 2018-12-12 EP disclosed
EP-3141901-A1 ANALYSIS DEVICE, AND ANALYSIS APPARATUS AND METHOD USING THE SAME Panasonic Healthcare Holdings Co., Ltd. (JP) 2017-03-15 EP disclosed
EP-2209008-B1 ANALYSIS DEVICE, AND ANALYSIS APPARATUS AND METHOD USING THE SAME PANASONIC HEALTHCARE HOLDINGS CO LTD (JP) 2016-12-21 EP disclosed
US-9151765-B2 Method for producing agglutinating reagent, agglutinating reagent or product produced thereby, and method for measuring analysis object using the same, and test kit and analysis device PANASONIC HEALTHCARE HOLDINGS CO., LTD. (JP) 2015-10-06 US disclosed
US-8956879-B2 Analysis device and method using the same PANASONIC HEALTHCARE CO., LTD. (JP) 2015-02-17 US disclosed
US-20140017814-A1 METHOD FOR PRODUCING AGGLUTINATING REAGENT, AGGLUTINATING REAGENT OR PRODUCT PRODUCED THEREBY, AND METHOD FOR MEASURING ANALYSIS OBJECT USING THE SAME, AND TEST KIT AND ANALYSIS DEVICE PANASONIC CORPORATION (JP) 2014-01-16 US disclosed
US-8574913-B2 Method for measurement of hemoglobin and hemoglobin derivative, and measurement kit PANASONIC CORPORATION (JP) 2013-11-05 US disclosed
US-20130164763-A1 ANALYSIS DEVICE AND METHOD USING THE SAME PANASONIC CORPORATION (JP) 2013-06-27 US disclosed
US-8415140-B2 Analysis device, and analysis apparatus and method using the same PANASONIC CORPORATION (JP) 2013-04-09 US disclosed
EP-2211175-B1 METHOD FOR MEASUREMENT OF HEMOGLOBIN AND HEMOGLOBIN DERIVATIVE, AND MEASUREMENT KIT PANASONIC CORP (JP) 2012-04-25 EP disclosed
US-20100267048-A1 METHOD FOR MEASUREMENT OF HEMOGLOBIN AND HEMOGLOBIN DERIVATIVE, AND MEASUREMENT KIT PANASONIC CORPORATION (JP) 2010-10-21 US disclosed
US-20100221741-A1 ANALYSIS DEVICE, AND ANALYSIS APPARATUS AND METHOD USING THE SAME PANASONIC CORPORATION (JP) 2010-09-02 US disclosed
EP-2211175-A1 METHOD FOR MEASUREMENT OF HEMOGLOBIN AND HEMOGLOBIN DERIVATIVE, AND MEASUREMENT KIT Panasonic Corporation (JP) 2010-07-28 EP disclosed
EP-2209008-A1 ANALYSIS DEVICE, AND ANALYSIS APPARATUS AND METHOD USING THE SAME Panasonic Corporation (JP) 2010-07-21 EP disclosed