Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.71 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.71 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.70 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | KDM6B | O15054 | 1/20 | 0.51 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | FES | P07332 | 1/20 | 0.50 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.50 |
| ▸ | FLT4 | P35916 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.50 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.49 |
| ▸ | HTR7 | P34969 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2569220 | 0.92 | L3MBTL1 (0.70) | F2KCNH2GRIN2BL3MBTL1KCNH3 | |
| SCHEMBL8874370 | 0.89 | F2 (0.64) | F2KCNH2GRIN2BL3MBTL1KCNH3 | |
| SCHEMBL24375975 | 0.85 | L3MBTL1 (0.95) | F2KCNH2GRIN2BL3MBTL1KCNH3 | |
| SCHEMBL21186859 | 0.85 | L3MBTL1 (0.95) | F2KCNH2GRIN2BL3MBTL1KCNH3 | |
| SCHEMBL11653014 | 0.85 | L3MBTL1 (0.86) | F2KCNH2GRIN2BL3MBTL1GAA | |
| SCHEMBL88597 | 0.85 | L3MBTL1 (0.95) | F2KCNH2GRIN2BL3MBTL1KCNH3 | |
| Hydrochloric Acid SCHEMBL8746161 | 0.83 | L3MBTL1 (1.00) | F2KCNH2GRIN2BL3MBTL1KCNH3 | |
| SCHEMBL12443081 | 0.81 | F2 (0.89) | F2KCNH2GRIN2BL3MBTL1KCNH3 | |
| SCHEMBL10055000 | 0.81 | L3MBTL1 (0.86) | F2KCNH2GRIN2BL3MBTL1KCNH3 | |
| SCHEMBL15904401 | 0.79 | L3MBTL1 (0.63) | F2KCNH2GRIN2BL3MBTL1KCNH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0436630-B1 | POLYMER-SUPPORTED 4-(N-BENZYL-N-METHYLAMINO)PYRIDINE CATALYST AND PROCESS FOR SAME | REILLY IND INC (US) | 1995-12-20 | — | — | EP | claimed |
| JP-4189883-A | — | — | None | — | — | JP | disclosed |
| US-9951075-B2 | Pteridines useful as HCV inhibitors and methods for the preparation thereof | JANSSEN SCIENCES IRELAND UC (IE) | 2018-04-24 | — | — | US | disclosed |
| US-20170275288-A1 | PTERIDINES USEFUL AS HCV INHIBITORS AND METHODS FOR THE PREPARATION THEREOF | JANSSEN SCIENCES IRELAND UC (IE) | 2017-09-28 | — | — | US | disclosed |
| US-9708328-B2 | Pteridines useful as HCV inhibitors and methods for the preparation thereof | JANSSEN SCIENCES IRELAND UC (IE) | 2017-07-18 | — | — | US | disclosed |
| US-20160158238-A1 | Pteridines Useful As HCV Inhibitors And Methods For The Preparation Thereof | Janssen Sciencies Ireland UC (IE) | 2016-06-09 | — | — | US | disclosed |
| US-20160159803-A1 | Pteridines Useful As HCV Inhibitors And Methods For The Preparation Thereof | Janssen Sciences Ireland Unlimited Company (IE) | 2016-06-09 | — | — | US | disclosed |
| US-9290502-B2 | Pteridines useful as HCV inhibitors and methods for the preparation thereof | JANSSEN SCIENCES IRELAND UC (IE) | 2016-03-22 | — | — | US | disclosed |
| EP-2948135-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF PERVASIVE DEVELOPMENT DISORDERS | Case Western Reserve University (US) | 2015-12-02 | — | — | EP | disclosed |
| WO-2014117089-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF PERVASIVE DEVELOPMENT DISORDERS | CASE WESTERN RESERVE UNIVERSITY (US) | 2014-07-31 | — | — | WO | disclosed |
| CN-101171014-A | Pteridines useful as HCV inhibitors and methods for the preparation thereof | TIBOTEC PHARM LTD (IE) | 2008-04-30 | — | — | CN | disclosed |
| EP-1881834-A1 | PTERIDINES USEFUL AS HCV INHIBITORS AND METHODS FOR THE PREPARATION THEREOF | Tibotec Pharmaceuticals Ltd. (IE) | 2008-01-30 | — | — | EP | disclosed |
| WO-2006120251-A1 | PTERIDINES USEFUL AS HCV INHIBITORS AND METHODS FOR THE PREPARATION THEREOF | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2006-11-16 | — | — | WO | disclosed |
| JP-2004238380-A | 4-PHENETHYLAMINOPYRIMIDINE DERIVATIVE, METHOD FOR PRODUCING THE SAME AND AGRICULTURAL OR HORTICULTURAL VERMIN-CONTROLLING AGENT | UBE IND LTD | 2004-08-26 | — | — | JP | disclosed |
| US-5597836-A | NEMATOCIDES, INSECTICIDES, MITICIDES AND PLANT PATHOGENS | DOWELANCO (US) | 1997-01-28 | — | — | US | disclosed |
| EP-0555469-A4 | 4-(ARALKOXY OR ARALKYLAMINO)PYRIDINE PESTICIDES----------------- | DOWELANCO (US) | 1995-06-21 | — | — | EP | disclosed |
| US-5399564-A | N-(4-pyridyl or 4-quinolinyl) arylacetamide and 4-(aralkoxy or aralkylamino) pyridine pesticides | DOWELANCO (US) | 1995-03-21 | — | — | US | disclosed |
| EP-0555469-A1 | 4-(ARALKOXY OR ARALKYLAMINO)PYRIDINE PESTICIDES----------------- | DOWELANCO (US) | 1993-08-18 | — | — | EP | disclosed |
| WO-1993005050-A1 | 4-(ARALKOXY OR ARALKYLAMINO)PYRIDINE PESTICIDES_________________ | DOWELANCO (US) | 1993-03-18 | — | — | WO | disclosed |
| JP-H04189883-A | ADHESIVE HAVING ANISOTROPIC ELECTRICAL CONDUCTIVITY | HITACHI CHEM CO LTD | 1992-07-08 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160159803-A1 | Pteridines Useful As HCV Inhibitors And Methods For The Preparation Thereof | HCCS, HAVCR2, MAVS | F2 884/4885KCNH2 4482/4885GRIN2B 4586/4885 |
| US-20170275288-A1 | PTERIDINES USEFUL AS HCV INHIBITORS AND METHODS FOR THE PREPARATION THEREOF | HCCS, HAVCR2, MAVS | F2 884/4885KCNH2 4482/4885GRIN2B 4586/4885 |
| US-20160158238-A1 | Pteridines Useful As HCV Inhibitors And Methods For The Preparation Thereof | HCCS, HAVCR2, MAVS | F2 884/4885KCNH2 4482/4885GRIN2B 4586/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.