Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CAPN9 | O14815 | 1/20 | 0.45 |
| ▸ | CAPN1 | P07384 | 5/20 | 0.44 |
| ▸ | CTSL | P07711 | 3/20 | 0.44 |
| ▸ | CTSB | P07858 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CTSG | P08311 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 3/20 | 0.42 |
| ▸ | CTSK | P43235 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.39 |
| ▸ | PPID | Q08752 | 2/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23619298 | 0.88 | ALDH1A1 (0.46) | ALDH1A1CAPN9CAPN1CTSLCTSB | |
| SCHEMBL23619297 | 0.88 | ALDH1A1 (0.49) | ALDH1A1CAPN9CAPN1CTSLCTSB | |
| SCHEMBL18930768 | 0.88 | KMT2A (0.52) | ALDH1A1CAPN9CAPN1CTSLCTSB | |
| SCHEMBL21248160 | 0.86 | ALDH1A1 (0.53) | ALDH1A1CAPN1CTSLCTSBCTSS | |
| SCHEMBL21248161 | 0.86 | ALDH1A1 (0.53) | ALDH1A1CAPN1CTSLCTSBCTSS | |
| SCHEMBL6756063 | 0.84 | CAPN9 (0.43) | CAPN9CAPN1CTSLCTSBLMNA | |
| SCHEMBL24301981 | 0.84 | CAPN9 (0.38) | ALDH1A1CAPN9CAPN1CTSLCTSB | |
| SCHEMBL21248186 | 0.83 | ALDH1A1 (0.50) | ALDH1A1CAPN9CAPN1CTSLCTSB | |
| SCHEMBL12572526 | 0.83 | SMN1; SMN2 (0.47) | ALDH1A1GAAPPIDMGAMSI | |
| SCHEMBL16628812 | 0.83 | CAPN9 (0.42) | CAPN9CAPN1CTSLCTSBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019157338-A1 | MEBENDAZOLE PRODRUGS WITH ENHANCED SOLUBILITY AND ORAL BIOAVAILABILITY | THE JOHNS HOPKINS UNIVERSITY (US) | 2019-08-15 | — | — | WO | disclosed |