SCHEMBL2126759

SCHEMBL2126759

CN(C)c1ccccc1/C=C/c1ccc([N+](=O)[O-])cc1

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SNCA P37840 4/20 0.50
CYP19A1 P11511 2/20 0.50
RAB9A P51151 3/20 0.49
MAPT P10636 3/20 0.49
NPC1 O15118 2/20 0.49
APP P05067 1/20 0.49
SMN1; SMN2 Q16637 2/20 0.48
FBP1 P09467 1/20 0.47
TLR9 Q9NR96 1/20 0.47
PTGS2 P35354 6/20 0.47
PTGS1 P23219 2/20 0.47
MAPK1 P28482 1/20 0.46
HTT P42858 1/20 0.46
BCHE P06276 1/20 0.46
MAOB P27338 1/20 0.46
NFE2L2 Q16236 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2126765 1.00 SNCA (0.50) SNCACYP19A1RAB9AMAPTNPC1
SCHEMBL10940074 0.84 CYP19A1 (0.62) SNCACYP19A1RAB9AMAPTNPC1
SCHEMBL11299294 0.84 CYP19A1 (0.62) SNCACYP19A1RAB9AMAPTNPC1
SCHEMBL8722439 0.82 MEN1 (0.57) SNCACYP19A1RAB9AMAPTNPC1
SCHEMBL8722431 0.82 MEN1 (0.57) SNCACYP19A1RAB9AMAPTNPC1
SCHEMBL31410688 0.82 NFE2L2 (0.56) SNCACYP19A1RAB9AMAPTNPC1
SCHEMBL28063092 0.81 ALDH1A1 (0.42) SNCARAB9AMAPTNPC1SMN1; SMN2
SCHEMBL1005679 0.80 SOS1 (0.54) CYP19A1RAB9AMAPTNPC1SMN1; SMN2
SCHEMBL14506296 0.80 CYP19A1 (0.54) SNCACYP19A1RAB9AMAPTNPC1
SCHEMBL9826818 0.80 CYP19A1 (0.54) SNCACYP19A1RAB9AMAPTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3314022-A1 EGFR ASSAY Abbott Molecular Inc. (US) 2018-05-02 EP disclosed
WO-2016210147-A1 EGFR ASSAY ABBOTT MOLECULAR INC. (US) 2016-12-29 WO disclosed
EP-2443683-A1 WRAPPED OPTOELECTRONIC DEVICES AND METHODS FOR MAKING SAME University Of Houston (US) 2012-04-25 EP disclosed
WO-2010148024-A1 WRAPPED OPTOELECTRONIC DEVICES AND METHODS FOR MAKING SAME UNIVERSITY OF HOUSTON (US) 2010-12-23 WO disclosed
EP-2203568-A1 A METHOD AND SYSTEM FOR OBTAINING ORDERED, SEGMENTED SEQUENCE FRAGMENTS ALONG A NUCLEIC ACID MOLECULE Life Technologies Corporation (US) 2010-07-07 EP disclosed
EP-2179006-A1 INORGANIC-ORGANIC COMPOSITE FLUORESCENT SUBSTANCE Karlsruher Institut für Technologie (DE) 2010-04-28 EP disclosed
WO-2009100800-A1 INORGANIC-ORGANIC COMPOSITE FLUORESCENT SUBSTANCE UNIVERSITÄT KARLSRUHE (TH) (DE) 2009-08-20 WO disclosed
WO-2009070766-A2 FUNCTIONALIZATION OF MICRO-AND NANO PARTICLES FOR SELECTIVE ATTACHMENT TO CALCIUM BIOMINERAL SURFACES BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2009-06-04 WO disclosed
WO-2009055508-A1 A METHOD AND SYSTEM FOR OBTAINING ORDERED, SEGMENTED SEQUENCE FRAGMENTS ALONG A NUCLEIC ACID MOLECULE Life Technologies Corporation (US) 2009-04-30 WO disclosed
US-4894263-A Mesomorphic polymer material usable in non linear optics THOMSON-CSF (FR) 1990-01-16 US disclosed
EP-0338845-A2 Nonlinear optical materials NIPPON OIL CO., LTD. (JP) 1989-10-25 EP disclosed