SCHEMBL212681

SCHEMBL212681

CC(C)=C(C)C(=O)OCCC(C=O)(C=O)C=O

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CHRM5 P08912 1/20 0.31
CHRM1 P11229 1/20 0.31
CHRM3 P20309 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6131315 0.80
SCHEMBL9854151 0.78 CHRM5 (0.34) CHRM5CHRM1CHRM3
SCHEMBL241532 0.78 CHRM5 (0.34) CHRM5CHRM1CHRM3
SCHEMBL7772992 0.74 CHRM5 (0.32) CHRM5CHRM1CHRM3
SCHEMBL23637 0.74 CHRM5 (0.32) CHRM5CHRM1CHRM3
SCHEMBL11599572 0.74 CHRM5 (0.32) CHRM5CHRM1CHRM3
SCHEMBL8977855 0.74 THRB (0.33) CHRM5CHRM1CHRM3
SCHEMBL10391730 0.73 CHRM5 (0.31) CHRM5CHRM1CHRM3
SCHEMBL3420729 0.73 CHRM5 (0.31) CHRM5CHRM1CHRM3
SCHEMBL1200078 0.72 CHRM5 (0.31) CHRM5CHRM1CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 429 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4121802-B1 HIGH REFRACTIVE INDEX SILOXANE INSERT MATERIALS FOR EMBEDDED CONTACT LENSES ALCON INC (CH) 2024-07-17 EP claimed
EP-4356169-A1 MULTIFOCAL DIFFRACTIVE SILICONE HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2024-04-24 EP claimed
EP-4121801-B1 INSERT MATERIALS WITH HIGH OXYGEN PERMEABILITY AND HIGH REFRACTIVE INDEX ALCON INC (CH) 2024-04-17 EP claimed
EP-2828692-B1 HYDROPHILIC MACROMERS AND HYDROGELS COMPRISING THE SAME MOMENTIVE PERFORMANCE MAT INC (US) 2024-02-28 EP claimed
US-11867874-B2 Insert materials with high oxygen permeability and high refractive index ALCON INC. (CH) 2024-01-09 US claimed
US-11845838-B2 Compositions and methods for crosslinking polymers in the presence of atmospheric oxygen ARKEMA INC. (US) 2023-12-19 US claimed
WO-2023218324-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC. (CH) 2023-11-16 WO claimed
US-20230357478-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC. (CH) 2023-11-09 US claimed
WO-2023209570-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC. (CH) 2023-11-02 WO claimed
US-20230339149-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC. (CH) 2023-10-26 US claimed
WO-2013142060-A1 HYDROPHILIC SILICONE MONOMERS, PROCESS FOR PREPARATION THEREOF AND THIN FILMS CONTAINING THE SAME MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2013-09-26 WO claimed
WO-2013142061-A1 HYDROPHILIC MACROMERS AND HYDROGELS COMPRISING THE SAME MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2013-09-26 WO claimed
US-20120245249-A1 SILOXANE MONOMERS CONTAINING HYDROLYSIS RESISTANCE CARBOSILOXANE LINKAGE, PROCESS FOR THEIR PREPARATION AND THIN FILMS CONTAINING THE SAME FOR CONTACT LENS APPLICATION MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-09-27 US claimed
WO-2012128752-A1 SILOXANE MONOMERS CONTAINING HYDROLYSIS RESISTANCE CARBOSILOXANE LINKAGE, PROCESS FOR THEIR PREPARATION AND THIN FILMS CONTAINING THE SAME FOR CONTACT LENS APPLICATION MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-09-27 WO claimed
EP-1393705-B9 Dental restorative compounds KERR CORP (US) 2009-12-16 EP claimed
EP-1393705-B1 Dental restorative compounds KERR CORP (US) 2009-02-25 EP claimed
US-20080038832-A1 Method for Producing Molecularly Imprinted Polymers for the Recognition of Target Molecules MIP TECHNOLOGIES AB 2008-02-14 US claimed
EP-1802969-A1 METHOD FOR PRODUCING MOLECULARLY IMPRINTED POLYMERS FOR THE RECOGNITION OF TARGET MOLECULES MIP Technologies AB (SE) 2007-07-04 EP claimed
WO-2006041398-A1 METHOD FOR PRODUCING MOLECULARLY IMPRINTED POLYMERS FOR THE RECOGNITION OF TARGET MOLECULES MIP TECHNOLOGIES AB (SE) 2006-04-20 WO claimed
US-20020002259-A1 LOW-ODOR, COLD-CURING (METH) ACRYLATE REACTION RESIN FOR FLOOR COATING, A FLOOR COATING CONTAINING THE REACTION RESIN, AND A PROCESS FOR THE PREPARATION OF THE FLOOR COATING ROEHM GMBH & CO KG (DE) 2002-01-03 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120245249-A1 SILOXANE MONOMERS CONTAINING HYDROLYSIS RESISTANCE CARBOSILOXANE LINKAGE, PROCESS FOR THEIR PREPARATION AND THIN FILMS CONTAINING THE SAME FOR CONTACT LENS APPLICATION SMCHD1, USP39, SUMO1 CHRM5 661/4885CHRM1 380/4885CHRM3 691/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.