Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.41 |
| ▸ | MAPKAPK2 | P49137 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.37 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21268430 | 0.89 | CYP17A1 (0.40) | MAPKAPK2CYP17A1SREBF2CA12CA1 | |
| SCHEMBL21268300 | 0.89 | HTT (0.39) | FAAHMAPKAPK2MAPTALDH1A1CYP17A1 | |
| SCHEMBL21268303 | 0.88 | MAPKAPK2 (0.38) | MAPKAPK2CYP17A1CA12CA1CA2 | |
| SCHEMBL21268155 | 0.83 | ALDH1A1 (0.39) | MAPTSMN1; SMN2ALDH1A1GAACYP17A1 | |
| SCHEMBL21268260 | 0.83 | MEN1 (0.44) | MAPKAPK2MAPTSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL21268384 | 0.82 | CA12 (0.43) | MAPKAPK2ALDH1A1GAACYP17A1CA12 | |
| SCHEMBL21268173 | 0.81 | ELANE (0.42) | MAPKAPK2CYP17A1CA12CA1CA9 | |
| SCHEMBL21268417 | 0.81 | CYP17A1 (0.37) | MAPTSMN1; SMN2ALDH1A1CYP17A1LMNA | |
| SCHEMBL13637520 | 0.80 | FAAH (0.62) | FAAHMAPTALDH1A1GAA | |
| SCHEMBL21268402 | 0.80 | ALDH1A1 (0.39) | SMN1; SMN2ALDH1A1GAACYP17A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-B1 | HERBICIDAL AND FUNGICIDAL 3-PHENYLISOXAZOLIN DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2019-08-21 | — | — | EP | disclosed |