Medronic Acid

Medronic Acid

SCHEMBL2126902

NCCNCCN.O=P(O)(O)CP(=O)(O)O.O=P(O)(O)CP(=O)(O)O.O=P(O)(O)CP(=O)(O)O.O=P(O)(O)CP(=O)(O)O.O=P(O)(O)CP(=O)(O)O.[Na]

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 1/20 0.54
CA12 O43570 4/20 0.50
CA6 P23280 4/20 0.50
CA7 P43166 4/20 0.50
CA9 Q16790 4/20 0.50
CA14 Q9ULX7 4/20 0.50
CA5B Q9Y2D0 4/20 0.50
KDM4E B2RXH2 2/20 0.50
HSD17B10 Q99714 2/20 0.50
MEN1 O00255 2/20 0.50
RECQL P46063 2/20 0.50
KMT2A Q03164 2/20 0.50
MMP2 P08253 1/20 0.50
THRB P10828 1/20 0.50
MAPK1 P28482 1/20 0.50
LMNA P02545 3/20 0.48
CA2 P00918 3/20 0.48
CA4 P22748 3/20 0.48
CA5A P35218 3/20 0.48
TDP1 Q9NUW8 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Medronic Acid SCHEMBL10628874 1.00 ANPEP (0.54) ANPEPCA12CA6CA7CA9
Medronic Acid SCHEMBL9347974 0.97 ANPEP (0.56) ANPEPCA12CA6CA7CA9
Medronic Acid SCHEMBL7081257 0.97 ANPEP (0.56) ANPEPCA12CA6CA7CA9
Medronic Acid SCHEMBL3889431 0.97 ANPEP (0.56) ANPEPCA12CA6CA7CA9
Medronic Acid SCHEMBL1138068 0.97 ANPEP (0.56) ANPEPCA12CA6CA7CA9
Medronic Acid SCHEMBL220473 0.97 ANPEP (0.56) ANPEPCA12CA6CA7CA9
Medronic Acid SCHEMBL1496457 0.97 ANPEP (0.56) ANPEPCA12CA6CA7CA9
Medronic Acid SCHEMBL2944253 0.95 ANPEP (0.54) ANPEPCA12CA6CA7CA9
Trientine SCHEMBL9564313 0.95 CA12 (0.55) ANPEPCA12CA6CA7CA9
Trientine SCHEMBL242925 0.95 CA12 (0.55) ANPEPCA12CA6CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2100002-B1 SCALE SQUEEZE TREATMENT METHODS AND SYSTEMS RHODIA (US) 2012-04-25 EP claimed
EP-0245557-A2 Stabilized antifreeze/coolant composition containing borate and silicate corrosion inhibitors TEXACO DEVELOPMENT CORPORATION (US) 1987-11-19 EP claimed
EP-3092214-B1 NITROSAMINE/NITRITE INHIBITION IN TERTIARY ALKYLAMINE OXIDE COMPOSITIONS EOC SURFACTANTS N V (BE) 2018-06-20 EP disclosed
EP-2534184-B1 RHEOLOGY MODIFIER POLYMER RHODIA OPERATIONS (FR) 2017-09-27 EP disclosed
EP-3092214-A2 NITROSAMINE/NITRITE INHIBITION IN TERTIARY ALKYLAMINE OXIDE COMPOSITIONS EOC Surfactants N.V. (BE) 2016-11-16 EP disclosed
WO-2015104673-A9 NITROSAMINE/NITRITE INHIBITION IN TERTIARY ALKYLAMINE OXIDE COMPOSITIONS EOC SURFACTANTS NV (BE) 2016-01-07 WO disclosed
US-9090727-B2 Rheology modifier polymer RHODIA OPERATIONS (FR) 2015-07-28 US disclosed
US-20140301966-A1 RHEOLOGY MODIFIER POLYMER SPECIALTY OPERATIONS FRANCE (FR) 2014-10-09 US disclosed
US-8784786-B2 Rheology modifier polymer RHODIA OPERATIONS (FR) 2014-07-22 US disclosed
EP-2534184-A1 RHEOLOGY MODIFIER POLYMER Rhodia Operations (FR) 2012-12-19 EP disclosed
US-20110243873-A1 Rheology modifier polymer RHODIA OPERATIONS (FR) 2011-10-06 US disclosed
WO-2011100071-A1 RHEOLOGY MODIFIER POLYMER RHODIA OPERATIONS (FR) 2011-08-18 WO disclosed
EP-0245557-A2 Stabilized antifreeze/coolant composition containing borate and silicate corrosion inhibitors TEXACO DEVELOPMENT CORPORATION (US) 1987-11-19 EP disclosed
US-4657689-A MONOBASIC AND DIBASIC ACIDS OR SALTS, TRIAZOLES TEXACO INC. (US) 1987-04-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140301966-A1 RHEOLOGY MODIFIER POLYMER C1R, PUF60, C9 ANPEP 4530/4885CA12 2332/4885CA6 2611/4885
US-20110243873-A1 Rheology modifier polymer C1R, PUF60, C9 ANPEP 4530/4885CA12 2332/4885CA6 2611/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.