Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 7/20 | 0.35 |
| ▸ | LGMN | Q99538 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | EED | O75530 | 2/20 | 0.34 |
| ▸ | MDM4 | O15151 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4626293 | 0.99 | GAA (0.40) | GAARAD52MTNR1AMTNR1BHRH4 | |
| Hydrochloric Acid SCHEMBL4626282 | 0.99 | GAA (0.40) | GAARAD52MTNR1AMTNR1BHRH4 | |
| SCHEMBL2126969 | 0.86 | GAA (0.44) | GAARAD52MTNR1AMTNR1BHRH4 | |
| Hydrochloric Acid SCHEMBL4627803 | 0.85 | GAA (0.43) | GAARAD52MTNR1AMTNR1BHRH4 | |
| Hydrochloric Acid SCHEMBL4627790 | 0.85 | GAA (0.43) | GAARAD52MTNR1AMTNR1BHRH4 | |
| SCHEMBL2127975 | 0.85 | GFER (0.38) | GAARAD52MTNR1AMTNR1BHRH4 | |
| Hydrochloric Acid SCHEMBL4625068 | 0.84 | KDM4E (0.38) | GAARAD52MTNR1AMTNR1BHRH4 | |
| SCHEMBL6504795 | 0.78 | GAA (0.51) | GAARAD52HRH4LGMN | |
| SCHEMBL7242505 | 0.76 | SUV39H2 (0.50) | SUV39H2 | |
| SCHEMBL6285772 | 0.74 | AKT1 (0.48) | GAARAD52SUV39H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1348695-B1 | Derivatives of paraphenylene diamine with pyrrolidine groups substituted by cationic radicals and their use for dyeing keratinic fibre | OREAL (FR) | 2012-04-25 | — | — | EP | claimed |
| EP-1428515-B1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a surfactant; methods and uses | OREAL (FR) | 2008-07-02 | — | — | EP | claimed |
| EP-1428514-B1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, a tertiary paraphenylenediamine and a benzomorpholine coupler; method and use | OREAL (FR) | 2007-09-19 | — | — | EP | claimed |
| US-6946005-B2 | Pyrrolidinyl-substituted para-phenylenediamine derivatives substituted with a cationic radical, and use of these derivatives for dyeing keratin fibers | L'OREAL S.A. (FR) | 2005-09-20 | — | — | US | claimed |
| US-20040205904-A1 | Dye composition comprising a cationic tertiary para-phenylenediamine and a vitamin derivative, processes therefor and uses thereof | L'OREAL (FR) | 2004-10-21 | — | — | US | claimed |
| US-20040205903-A1 | Dyeing composition comprising a cationic pyrrolidine-based para-phenylenefiamine, a tertiary para-phenylenediamine and a benzomorpholine coupler, methods and uses | L'OREAL (FR) | 2004-10-21 | — | — | US | claimed |
| US-20040194227-A9 | Pyrrolidinyl-substituted para-phenylenediamine derivatives substituted with a cationic radical, and use of these derivatives for dyeing keratin fibres | L'OREAL S.A. (FR) | 2004-10-07 | — | — | US | claimed |
| EP-1428508-A1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a monosaccharide or disaccharide ; method and use | L'OREAL (FR) | 2004-06-16 | — | — | EP | claimed |
| EP-1428515-A1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a surfactant; method and use | L'OREAL (FR) | 2004-06-16 | — | — | EP | claimed |
| EP-1428513-A1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a opacifying or pearlescent agent; method and use | L'OREAL (FR) | 2004-06-16 | — | — | EP | claimed |
| EP-1428507-A1 | Dyeing composition containing a tertiary cationic paraphenylendiamine and an organic diacid, process and use | L'OREAL (FR) | 2004-06-16 | — | — | EP | claimed |
| EP-1428517-A1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a vitamine derivative; method and use | L'OREAL (FR) | 2004-06-16 | — | — | EP | claimed |
| EP-1428506-A1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a polymere containing a fatty chain; method and use | L'OREAL (FR) | 2004-06-16 | — | — | EP | claimed |
| EP-1428516-A1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a polyol ester; method and use | L'OREAL (FR) | 2004-06-16 | — | — | EP | claimed |
| EP-1428510-A1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a heterocyclic coupler or a hydroxybenzamide ; method and use | L'OREAL (FR) | 2004-06-16 | — | — | EP | claimed |
| EP-1428512-A1 | Dyeing composition containing a tertiary cationic paraphenylendiamine and a paraaminophenol, process and use | L'OREAL (FR) | 2004-06-16 | — | — | EP | claimed |
| EP-1428505-A1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a cationic direct dye containing a heterocyclic group ; method and use | L'OREAL (FR) | 2004-06-16 | — | — | EP | claimed |
| EP-1428511-A1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a cationic polymer; method and use | L'OREAL (FR) | 2004-06-16 | — | — | EP | claimed |
| US-20030229949-A1 | Pyrrolidinyl-substituted para-phenylenediamine derivatives substituted with a cationic radical, and use of these derivatives for dyeing keratin fibres | SABELLE STEPHANE (FR) | 2003-12-18 | — | — | US | claimed |
| EP-1348695-A1 | Derivatives of paraphenylene diamine with pyrrolidine groups substituted by cationic radicals and their use for dyeing keratinic fibre | L'OREAL (FR) | 2003-10-01 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040205903-A1 | Dyeing composition comprising a cationic pyrrolidine-based para-phenylenefiamine, a tertiary para-phenylenediamine and a benzomorpholine coupler, methods and uses | CDC73, KRT18, PAH | GAA 4851/4885RAD52 290/4885MTNR1A 556/4885 |
| US-20040194227-A9 | Pyrrolidinyl-substituted para-phenylenediamine derivatives substituted with a cationic radical, and use of these derivatives for dyeing keratin fibres | KRT18, VIM, CKAP4 | GAA 4822/4885RAD52 651/4885MTNR1A 2865/4885 |
| US-20030229949-A1 | Pyrrolidinyl-substituted para-phenylenediamine derivatives substituted with a cationic radical, and use of these derivatives for dyeing keratin fibres | KRT18, VIM, CKAP4 | GAA 4822/4885RAD52 651/4885MTNR1A 2865/4885 |
| US-20040205904-A1 | Dye composition comprising a cationic tertiary para-phenylenediamine and a vitamin derivative, processes therefor and uses thereof | KRT18, PPHLN1, PYCR1 | GAA 4705/4885RAD52 1134/4885MTNR1A 2138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.