Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.61 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.54 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.54 |
| ▸ | ABAT | P80404 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31318322 | 0.86 | TUBB1 (0.55) | MEN1KMT2ASLC22A6SLC22A8RAB9A | |
| SCHEMBL10674510 | 0.86 | TSHR (0.58) | KMT2AALDH1A1HPGDPOLBGAA | |
| SCHEMBL2937667 | 0.84 | MEN1 (0.58) | MEN1KMT2ASLC22A6SLC22A8RAB9A | |
| SCHEMBL19655666 | 0.81 | SLC22A6 (0.68) | MEN1KMT2ASLC22A6SLC22A8RAB9A | |
| SCHEMBL4649592 | 0.78 | MEN1 (0.63) | MEN1KMT2ASLC22A6SLC22A8RAB9A | |
| SCHEMBL18776640 | 0.78 | HTT (0.67) | MEN1KMT2ASLC22A6SLC22A8RAB9A | |
| SCHEMBL2221669 | 0.77 | CA12 (0.50) | RAB9AKDM4EPOLBHDAC6GAA | |
| SCHEMBL25362422 | 0.77 | KMT2A (0.62) | MEN1KMT2ASLC22A6SLC22A8RAB9A | |
| SCHEMBL7122113 | 0.77 | TUBB1 (0.54) | MEN1KMT2AHTTGAAMAPT | |
| Methyl Vanillate SCHEMBL275939 | 0.77 | KMT2A (0.72) | MEN1KMT2ASLC22A6SLC22A8RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120135456-A1 | METHOD AND KIT FOR DETECTION OF GUAIACOL-PRODUCING BACTERIUM | CALPIS CO., LTD. (JP) | 2012-05-31 | — | — | US | claimed |
| EP-2444502-A1 | METHOD AND KIT FOR DETECTION OF GUAIACOL-PRODUCING BACTERIUM | Calpis Co., Ltd. (JP) | 2012-04-25 | — | — | EP | claimed |
| EP-3150203-B1 | COMPOUNDS WITH (1E,6E)-1,7-BIS-(3,4- DIMETHOXYPHENYL)-4,4-DISSTITUTED-HEPA-1,6-DIENE-3,5-DI-ONE STRUCTURAL SCAFFOLD,THEIR BIOLOGICAL ACTIVITY, AND USES THEREOF | ALLIANZ PHARMASCIENCE LTD (TW) | 2020-02-19 | — | — | EP | disclosed |
| EP-3549581-A2 | COMPOUNDS WITH (1E, 6E)-1,7-BIS-(3,4-DIMETHOXYPHENYL)-4,4-DISSTITUTED-HEPA-1,6-DIENE-3,5-DIONE STRUCTURAL SCAFFOLD, THEIR BIOLOGICAL ACTIVITY, AND USES THEREOF | Allianz Pharmascience Ltd (TW) | 2019-10-09 | — | — | EP | disclosed |
| CN-110279680-A | A kind of medical composition and its use | 有联生技股份有限公司 | 2019-09-27 | — | — | CN | disclosed |
| EP-2993165-B1 | COMPOUNDS WITH (SUBSTITUTED PHENYL)-PROPENAL MOIETY, THEIR DERIVATIVES, BIOLOGICAL ACTIVITY, AND USE THEREOF | ALLIANZ PHARMASCIENCE LTD (TW) | 2018-06-27 | — | — | EP | disclosed |
| EP-3150203-A1 | COMPOUNDS WITH (1E,6E)-1,7-BIS-(3,4- DIMETHOXYPHENYL)-4,4-DISSTITUTED-HEPA-1,6-DIENE-3,5-DI-ONE STRUCTURAL SCAFFOLD,THEIR BIOLOGICAL ACTIVITY, AND USES THEREOF | Allianz Pharmascience Ltd (TW) | 2017-04-05 | — | — | EP | disclosed |
| US-9562025-B2 | Compounds with (1E, 6E)-1,7-Bis-(3,4-dimethoxyphenyl)-4-4-distributed-hepta-1,6-diene-3,5-dione structural scaffold, their biological activity, and uses thereof | ALLIANZ PHARMASCIENCE LTD. (TW) | 2017-02-07 | — | — | US | disclosed |
| CN-106220507-A | Compound with (1E,6E) -1, 7-bis- (3, 4-dimethoxyphenyl) -4, 4-disubstituted hepta-1, 6-diene-3, 5-dione structural framework and application thereof | 有联生技股份有限公司 | 2016-12-14 | — | — | CN | disclosed |
| US-20160264539-A1 | COMPOUNDS WITH (1E, 6E)-1,7-BIS-(3,4-DIMETHOXYPHENYL)-4-4-DISUBSTITUTED-HEPTA-1,6-DIENE-3,5-DIONE STRUCTURAL SCAFFOLD, THEIR BIOLOGICAL ACTIVITY, AND USES THEREOF | Annji Pharmaceutical Co., Ltd. (TW) | 2016-09-15 | — | — | US | disclosed |
| EP-2993165-A2 | COMPOUNDS WITH (SUBSTITUTED PHENYL)-PROPENAL MOIETY, THEIR DERIVATIVES, BIOLOGICAL ACTIVITY, AND USE THEREOF | Allianz Pharmascience Ltd (TW) | 2016-03-09 | — | — | EP | disclosed |
| US-20130261121-A1 | Compounds with (1E, 6E)-1,7-bis-(3,4-dimethoxyphenyl)-4,4-disubstituted-hepta-1,6-diene-3,5-dione structural scaffold, their biological activity, and uses thereof | Annji Pharmaceutical Co., Ltd. (TW) | 2013-10-03 | — | — | US | disclosed |
| US-8236852-B2 | Drugs/cosmetics having at least one (substituted phenyl)-propenal moiety; bioavailability' water solubility; antiandrogens; antiinflammatory and wound healing agents; antiarthritic agents; acne; alopecia, hirsutism; anticarcinogenic agents; cancer of the bladder, liver, breast; Kennedy's disease | ANDROSCIENCE CORPORATION (US) | 2012-08-07 | — | — | US | disclosed |
| US-8202905-B2 | Compounds with (substituted phenyl)-propenal moiety, their derivatives, biological activity, and use thereof | ANDROSCIENCE CORPORATION (US) | 2012-06-19 | — | — | US | disclosed |
| US-20120135456-A1 | METHOD AND KIT FOR DETECTION OF GUAIACOL-PRODUCING BACTERIUM | CALPIS CO., LTD. (JP) | 2012-05-31 | — | — | US | disclosed |
| EP-2444502-A1 | METHOD AND KIT FOR DETECTION OF GUAIACOL-PRODUCING BACTERIUM | Calpis Co., Ltd. (JP) | 2012-04-25 | — | — | EP | disclosed |
| US-20100292342-A1 | Compounds with (substituted phenyl)-propenal moiety, their derivatives, biological activity, and use thereof | Annji Pharmaceutical Co., Ltd. (TW) | 2010-11-18 | — | — | US | disclosed |
| EP-2104659-A1 | COMPOUNDS WITH (SUBSTITUTED PHENYL)-PROPENAL MOIETY, THEIR DERIVATIVES, BIOLOGICAL ACTIVITY, AND USES THEREOF | AndroScience Corporation (US) | 2009-09-30 | — | — | EP | disclosed |
| US-20080188557-A1 | Compounds with (substituted phenyl)-propenal moiety, their derivatives, biological activity, and use thereof | Annji Pharmaceutical Co., Ltd. (TW) | 2008-08-07 | — | — | US | disclosed |
| WO-2008085984-A1 | COMPOUNDS WITH (SUBSTITUTED PHENYL)-PROPENAL MOIETY, THEIR DERIVATIVES, BIOLOGICAL ACTIVITY, AND USES THEREOF | ANDROSCIENCE CORPORATION (US) | 2008-07-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292342-A1 | Compounds with (substituted phenyl)-propenal moiety, their derivatives, biological activity, and use thereof | AR, CYP17A1, CYP19A1 | MEN1 2395/4885KMT2A 1924/4885SLC22A6 4282/4885 |
| US-20080188557-A1 | Compounds with (substituted phenyl)-propenal moiety, their derivatives, biological activity, and use thereof | AR, CYP17A1, CYP19A1 | MEN1 2395/4885KMT2A 1924/4885SLC22A6 4282/4885 |
| US-20120135456-A1 | METHOD AND KIT FOR DETECTION OF GUAIACOL-PRODUCING BACTERIUM | APEH, GANC, AOC1 | MEN1 4172/4885KMT2A 1120/4885SLC22A6 3368/4885 |
| US-20130261121-A1 | Compounds with (1E, 6E)-1,7-bis-(3,4-dimethoxyphenyl)-4,4-disubstituted-hepta-1,6-diene-3,5-dione structural scaffold, their biological activity, and uses thereof | AR, BRCA1, CYP17A1 | MEN1 2785/4885KMT2A 2312/4885SLC22A6 4512/4885 |
| US-20160264539-A1 | COMPOUNDS WITH (1E, 6E)-1,7-BIS-(3,4-DIMETHOXYPHENYL)-4-4-DISUBSTITUTED-HEPTA-1,6-DIENE-3,5-DIONE STRUCTURAL SCAFFOLD, THEIR BIOLOGICAL ACTIVITY, AND USES THEREOF | AR, CYP17A1, SRD5A1 | MEN1 3405/4885KMT2A 2381/4885SLC22A6 4599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.