Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.58 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | AR | P10275 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2127017 | 0.84 | MEN1 (0.61) | MEN1KMT2ASLC22A6SLC22A8RAB9A | |
| SCHEMBL3751049 | 0.81 | SLC22A6 (0.66) | MEN1KMT2ASLC22A6SLC22A8RAB9A | |
| SCHEMBL18776640 | 0.79 | HTT (0.67) | MEN1KMT2ASLC22A6SLC22A8RAB9A | |
| SCHEMBL4649592 | 0.79 | MEN1 (0.63) | MEN1KMT2ASLC22A6SLC22A8RAB9A | |
| Vanillic Acid SCHEMBL26622368 | 0.78 | HTT (0.81) | MEN1KMT2ASLC22A6SLC22A8RAB9A | |
| SCHEMBL20897645 | 0.78 | SLC22A6 (0.62) | MEN1KMT2ASLC22A6SLC22A8RAB9A | |
| SCHEMBL28577289 | 0.77 | MEN1 (0.51) | MEN1KMT2ASLC22A6SLC22A8RAB9A | |
| Apocynin SCHEMBL31510122 | 0.77 | HTT (0.63) | MEN1KMT2ASLC22A6SLC22A8RAB9A | |
| SCHEMBL14394182 | 0.77 | CYP3A4 (0.39) | MEN1KMT2ASLC22A6SLC22A8RAB9A | |
| SCHEMBL12963319 | 0.77 | TSHR (0.60) | ALDH1A1HPGDGAAMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2087117-B1 | NEW KETOLASES FOR THE PRODUCTION OF KETOCAROTENOIDS IN TAGETES | BASF PLANT SCIENCE GMBH (DE) | 2010-09-15 | — | — | EP | disclosed |
| US-20100005541-A1 | KETOLASES FOR THE PRODUCTION OF KETOCAROTENOIDS IN TAGETES | BASF PLANT SCIENCE GMBH (DE) | 2010-01-07 | — | — | US | disclosed |
| EP-2087117-A1 | NEW KETOLASES FOR THE PRODUCTION OF KETOCAROTENOIDS IN TAGETES | BASF Plant Science GmbH (DE) | 2009-08-12 | — | — | EP | disclosed |
| EP-2032705-A2 | USE OF A PLASTID-LIPID ASSOCIATED PROTEIN PROMOTER (PAP PROMOTER) FOR HETEROLOGOUS GENE EXPRESSION | BASF Plant Science GmbH (DE) | 2009-03-11 | — | — | EP | disclosed |
| WO-2008058946-A1 | NEW KETOLASES FOR THE PRODUCTION OF KETOCAROTENOIDS IN TAGETES | BASF PLANT SCIENCE GMBH (DE) | 2008-05-22 | — | — | WO | disclosed |
| WO-2008058948-A1 | PLASTID-LIPID-ASSOCIATED PROTEIN PROMOTERS FOR THE PRODUCTION OF KETO-CAROTENOIDS IN TAGETES | BASF PLANT SCIENCE GMBH (DE) | 2008-05-22 | — | — | WO | disclosed |
| WO-2007144342-A2 | USE OF A PLASTID-LIPID ASSOCIATED PROTEIN PROMOTER (PAP PROMOTER) FOR HETEROLOGOUS GENE EXPRESSION | BASF PLANT SCIENCE GMBH (DE) | 2007-12-21 | — | — | WO | disclosed |
| US-20060162020-A1 | Promoters for the expression of genes in tagetes | SUNGENE GMBH (DE) | 2006-07-20 | — | — | US | disclosed |
| EP-1658371-A2 | PROMOTERS FOR THE EXPRESSION OF GENES IN TAGETES | Sungene GmbH & Co. KgAA (DE) | 2006-05-24 | — | — | EP | disclosed |
| WO-2005019460-A2 | PROMOTERS FOR THE EXPRESSION OF GENES IN TAGETES | SUNGENE GMBH (DE) | 2005-03-03 | — | — | WO | disclosed |