Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 19/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL982517 | 1.00 | HTR4 (0.51) | HTR4CNR1CNR2 | |
| SCHEMBL13538937 | 0.79 | HTR4 (0.49) | HTR4CNR1CNR2 | |
| SCHEMBL1572199 | 0.78 | HTR4 (0.50) | HTR4CNR1CNR2 | |
| SCHEMBL496159 | 0.77 | HTR4 (0.50) | HTR4CNR1CNR2 | |
| SCHEMBL984621 | 0.76 | HCRTR1 (0.42) | — | |
| SCHEMBL7951997 | 0.76 | HTR4 (0.64) | HTR4CNR1CNR2 | |
| Hydrochloric Acid SCHEMBL7956600 | 0.75 | HTR4 (0.63) | HTR4CNR1CNR2 | |
| SCHEMBL496447 | 0.75 | HTR4 (0.48) | HTR4CNR1CNR2 | |
| SCHEMBL10375846 | 0.74 | HTR4 (0.53) | HTR4CNR1CNR2 | |
| SCHEMBL983709 | 0.74 | CNR1 (0.51) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2247586-B1 | 2-AZA-BICYCLO[2.2.1]HEPTANE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2012-04-25 | — | — | EP | disclosed |