Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 18/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | POLR1A | O95602 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7951997 | 0.81 | HTR4 (0.64) | HTR4CNR1CNR2 | |
| Hydrochloric Acid SCHEMBL7956600 | 0.80 | HTR4 (0.63) | HTR4CNR1CNR2 | |
| SCHEMBL1572199 | 0.78 | HTR4 (0.50) | HTR4CNR1CNR2 | |
| SCHEMBL496159 | 0.78 | HTR4 (0.50) | HTR4CNR1CNR2 | |
| SCHEMBL11273600 | 0.76 | HTR4 (0.63) | HTR4 | |
| SCHEMBL31188533 | 0.75 | OPRM1 (0.56) | POLR1A | |
| SCHEMBL13538937 | 0.75 | HTR4 (0.49) | HTR4CNR1CNR2 | |
| SCHEMBL3643978 | 0.75 | HTR4 (0.59) | HTR4CNR1CNR2 | |
| SCHEMBL2127093 | 0.74 | HTR4 (0.51) | HTR4CNR1CNR2 | |
| SCHEMBL982517 | 0.74 | HTR4 (0.51) | HTR4CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0216658-B1 | BENZODIOXEPANE, PROCESS FOR ITS PREPARATION AND ITS THERAPEUTICAL USE | SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE-DE-FRANCE (FR) | 1990-01-31 | — | — | EP | disclosed |