SCHEMBL21274261

SCHEMBL21274261

C1=C(Cc2cccc(CC3=CCc4ccccc43)n2)c2ccccc2C1

nearest known ligand 0.54

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.54
KCNH2 Q12809 2/20 0.33
MAOA P21397 1/20 0.32
CHEK1 O14757 1/20 0.30
DAPK3 O43293 1/20 0.30
LTK P29376 1/20 0.30
MAPK8 P45983 1/20 0.30
CSNK1A1 P48729 1/20 0.30
CDK8 P49336 1/20 0.30
LIMK1 P53667 1/20 0.30
CDK5 Q00535 1/20 0.30
DYRK1A Q13627 1/20 0.30
LRRK2 Q5S007 1/20 0.30
CLK4 Q9HAZ1 1/20 0.30
DYRK1B Q9Y463 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30733631 1.00 HTR6 (0.54) HTR6KCNH2MAOACHEK1DAPK3
SCHEMBL29849641 0.83 HTR6 (0.51) HTR6
SCHEMBL1436947 0.83 HTR6 (0.51) HTR6
SCHEMBL7618202 0.82 HTR6 (0.67) HTR6KCNH2MAOA
SCHEMBL6130448 0.76 HTR6 (0.74) HTR6MAOA
SCHEMBL2338975 0.74 HTR6 (0.56) HTR6MAOA
SCHEMBL31121639 0.74 HTR6 (0.56) HTR6MAOA
SCHEMBL23160905 0.74 HTR6 (0.53) HTR6
SCHEMBL29602604 0.74 HTR6 (0.53) HTR6
SCHEMBL4444191 0.73 HTR6 (0.49) HTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3755705-B1 CATALYSTS, CATALYST SYSTEMS, AND METHODS FOR USING THE SAME EXXONMOBIL CHEMICAL PATENTS INC (US) 2024-09-04 EP disclosed
US-11440979-B2 Catalysts, catalyst systems, and methods for using the same EXXONMOBIL CHEMICAL PATENTS INC. (US) 2022-09-13 US disclosed
EP-3755705-A1 CATALYSTS, CATALYST SYSTEMS, AND METHODS FOR USING THE SAME ExxonMobil Chemical Patents Inc. (US) 2020-12-30 EP disclosed
US-20200339712-A1 Catalysts, Catalyst Systems, and Methods for Using the Same EXXONMOBIL CHEMICAL PATENTS INC (US) 2020-10-29 US disclosed
US-20200339712-A1 Catalysts, Catalyst Systems, and Methods for Using the Same EXXONMOBIL CHEMICAL PATENTS INC (US) 2020-10-29 US disclosed
WO-2019160710-A1 CATALYSTS, CATALYST SYSTEMS, AND METHODS FOR USING THE SAME EXXONMOBIL CHEMICAL PATENTS INC. (US) 2019-08-22 WO disclosed
WO-2019160710-A1 CATALYSTS, CATALYST SYSTEMS, AND METHODS FOR USING THE SAME EXXONMOBIL CHEMICAL PATENTS INC. (US) 2019-08-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11440979-B2 Catalysts, catalyst systems, and methods for using the same CYCS, CAT, PARG HTR6 3973/4885KCNH2 3976/4885MAOA 326/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.